(5E)-5-(4-Fluorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one CAS 402-93-7
| CAS No. | 402-93-7 |
| Molecular Formula | C10H6FNOS2 |
| Molecular Weight | 239.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (5E)-5-(4-Fluorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(5E)-5-(4-Fluorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one (CAS 402-93-7), molecular formula C10H6FNOS2 and molecular weight 239.29 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, (5E)-5-(4-Fluorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 239.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (5E)-5-(4-Fluorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6FNOS2 |
| Molecular Weight | 239.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related E Standards
- (E)-5-(2-Fluorobenzylidene)-2-mercaptothiazol-4(5H)-one (CAS 1784763-12-7)
- (Z)-5-(4-Fluorobenzylidene)-2-thioxothiazolidin-4-one (CAS 181765-53-7)
- (5E)-5-(3-Fluorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one (CAS 349-33-7)
- (Z)-5-(2-Fluorobenzylidene)-2-thioxothiazolidin-4-one (CAS 917985-95-6)
- 3-(4-Fluorobenzylidene)-2-indolinone (CAS 3476-86-6)
- (Z)-3-(4-Fluorobenzylidene)isobenzofuran-1(3H)-one (CAS 105279-30-9)
- (Z)-5-(4-fluorobenzylidene)-3-methylthiazolidine-2,4-dione (CAS 366483-72-9)
- 4-((2-Fluorobenzylidene)amino)-5-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 466644-97-3)
Recommended Standards
- (R)-4-((1-(3-fluoropropyl)pyrrolidin-3-yl)oxy)phenol (CAS 2409800-64-0)
- (4R)-2-(4-methoxyphenyl)thiazolidine-4-carboxylic acid (CAS 222404-25-3)
- (R)-N-Boc-2-fluoro-1-phenylethanamine (CAS 2006287-04-1)
- ({2-[methyl(phenyl)amino]-2-oxoethyl}thio)acetic acid (CAS 790232-20-1)
- 2-Chloro-3-(4-isopropylpiperazin-1-yl)pyrazine (CAS 651047-53-9)
- (2-Methyl-4-(1H-pyrazol-1-yl)phenyl)methanamine dihydrochloride (CAS 2138117-78-7)
- 4-((tert-Butoxycarbonyl)amino)nicotinic acid (CAS 171178-34-0)
- Ethyl 2-(2-chlorobenzamido)-4-methyl-5-(phenylcarbamoyl)thiophene-3-carboxylate (CAS 296244-50-3)
- Ethyl 5-amino-2-phenyl-3-sulfanylidene-2,3-dihydro-1,2-thiazole-4-carboxylate (CAS 380442-79-5)
- 3-(4-(Benzyloxy)phenyl)pentanedioicacid (CAS 165119-29-9)
- Olaparib (CAS 763113-22-0)
- 7-Nitro-2,3-dihydrobenzofuran-3-amine (CAS 1273665-67-0)
- 1-(Benzo[d][1,3]dioxol-5-yl)-2,2,3,3,3-pentafluoropropan-1-one (CAS 1443354-07-1)
- Semaglutide impurity 66 (CAS CATO-C4X-222666)
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