N-[4-(Trifluoromethyl)phenyl]acetamide CAS 349-97-3
| CAS No. | 349-97-3 |
| Molecular Formula | C9H8F3NO |
| Molecular Weight | 203.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), N-[4-(Trifluoromethyl)phenyl]acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
N-[4-(Trifluoromethyl)phenyl]acetamide (CAS 349-97-3), molecular formula C9H8F3NO and molecular weight 203.16 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, N-[4-(Trifluoromethyl)phenyl]acetamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 203.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H8F3NO |
| Molecular Weight | 203.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- 3-(3-(Trifluoromethyl)-1h-pyrazol-1-yl)butanenitrile (CAS 1006319-93-2)
- 3-(5-Methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)propanenitrile (CAS 1006343-68-5)
- 3-[3-methyl-5-(trifluoromethyl)-1h-pyrazol-1-yl]propanenitrile (CAS 1006461-11-5)
- 3-(Trifluoromethyl)-7,8-dihydro-5H-pyrano[4,3-b]pyridine (CAS 1196151-73-1)
- 1-(5-(Trifluoromethyl)pyridin-2-yl)propan-1-one (CAS 120427-48-7)
- 5-(Trifluoromethyl)-2,3-dihydro-1-benzofuran-3-amine (CAS 1243205-10-8)
- 6-(Trifluoromethyl)-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine (CAS 1260657-41-7)
- 2-(1-Ethyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)acetonitrile (CAS 1260659-32-2)
Recommended Standards
- 3-Oxo-3-(3-(trifluoromethyl)bicyclo[1.1.1]pentan-1-yl)propanenitrile (CAS 2737246-38-5)
- 4-Methyl-3-(trifluoromethyl)benzamide (CAS 261952-00-5)
- 3-Amino-1,1,1-trifluoro-3-phenylpropan-2-one (CAS 923256-36-4)
- 5-(Trifluoromethoxy)indoline (CAS 953906-76-8)
- (S)-1-(5-Phenyl-1H-imidazol-2-yl)ethanamine, 97% (CAS 864825-23-0)
- 2-Phenyl-1h-benzo[d]imidazole-6-sulfonic acid hydrate (CAS 207853-65-4)
- 2-(2-Methoxythiophen-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2073096-04-3)
- tert-Butyl (4-(hydroxymethyl)-2-iodophenyl)carbamate (CAS 755034-87-8)
- 3-Phenyl-1-(4-(trifluoromethyl)phenyl)propan-1-one (CAS 67082-00-2)
- 1,3,6,8-Tetramethoxyanthracene-9,10-dione (CAS 2476-76-8)
- 2-Amino-4-(4-fluorophenyl)-7-methyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile (CAS 315246-03-8)
- 4-Chloro-8-methyl-2-(trichloromethyl)quinoline (CAS 91991-86-5)
- 3-Methoxy-N-methyl-propanamide (CAS 38188-92-0)
- Galanin (1-13)-Neuropeptide Y (25-36) amide (CAS 147138-51-0)
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