5-(Trifluoromethoxy)indoline CAS 953906-76-8
| CAS No. | 953906-76-8 |
| Molecular Formula | C9H8F3NO |
| Molecular Weight | 203.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 5-(Trifluoromethoxy)indoline (CAS 953906-76-8), a certified reference material (molecular formula C9H8F3NO, MW 203.16 g/mol) for analytical method development and quality control.
The molecular framework of 5-(Trifluoromethoxy)indoline (C9H8F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 5-(Trifluoromethoxy)indoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8F3NO |
| Molecular Weight | 203.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethoxy Standards
- 5-(Trifluoromethoxy)-2,3-dihydro-1H-isoindole (CAS 1211532-42-1)
- 4-(Trifluoromethoxy)-2,3-dihydro-1H-isoindole (CAS 1895724-99-8)
- 6-(Trifluoromethoxy)indoline (CAS 959235-95-1)
- 7-(Trifluoromethoxy)indoline (CAS 953747-36-9)
- 2-(Trifluoromethoxy)pyrazine-6-acetonitrile (CAS 1261785-95-8)
- 5-(Trifluoromethoxy)benzoxazole (CAS 1520948-24-6)
- 5-(Trifluoromethoxy)-1H-benzo[d][1,2,3]triazole (CAS 157590-69-7)
- 2-(Trifluoromethoxy)phenyl Isocyanate (CAS 182500-26-1)
Recommended Standards
- 4-Methyl-3-(trifluoromethyl)benzamide (CAS 261952-00-5)
- 5-Methyl-2-(trifluoromethyl)benzamide (CAS 886502-71-2)
- N-[4-(Trifluoromethyl)phenyl]acetamide (CAS 349-97-3)
- 3-Oxo-3-(3-(trifluoromethyl)bicyclo[1.1.1]pentan-1-yl)propanenitrile (CAS 2737246-38-5)
- 1-(2,5-Dimethylbenzyl)azetidin-3-ol (CAS 1341583-66-1)
- 3-Methoxy-N-(2-methylbenzo[d]thiazol-6-yl)-2-naphthamide (CAS 313237-27-3)
- Ethyl (4-aminocyclohexyl)carbamate (CAS 850787-22-3)
- 2-Methylaminothioacetamide HCl (CAS 118020-65-8)
- 1-(3-Fluorobenzyl)piperidin-4-ol (CAS 184921-09-3)
- 4-Chloro-N-(4-(4-methylpiperazin-1-yl)phenyl)benzamide (CAS 303150-63-2)
- 3-(O-tolylthio)propanal (CAS 124829-84-1)
- 5-Acetamido-2-bromo-3-picoline (CAS 96206-67-6)
- 3-(4-methyl-2,5-dioxoimidazolidin-4-yl)benzene-1-sulfonamide (CAS 1258650-59-7)
- Liraglutide Impurity 13 TFA Salt (CAS CATO-C4X-199213)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com