(E)-N'-(1-(3-aminophenyl)ethylidene)-2-((1-bromonaphthalen-2-yl)oxy)acetohydrazide CAS 349468-16-2
| CAS No. | 349468-16-2 |
| Molecular Formula | C20H18BrN3O2 |
| Molecular Weight | 412.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (E)-N'-(1-(3-aminophenyl)ethylidene)-2-((1-bromonaphthalen-2-yl)oxy)acetohydrazide (CAS 349468-16-2), a certified reference material (molecular formula C20H18BrN3O2, MW 412.28 g/mol) for analytical method development and quality control.
The molecular framework of (E)-N'-(1-(3-aminophenyl)ethylidene)-2-((1-bromonaphthalen-2-yl)oxy)acetohydrazide (C20H18BrN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (E)-N'-(1-(3-aminophenyl)ethylidene)-2-((1-bromonaphthalen-2-yl)oxy)acetohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H18BrN3O2 |
| Molecular Weight | 412.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Recommended Standards
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