Dasatinib Impurity 6 CAS CATO-C4X-16076
| CAS No. | CATO-C4X-16076 |
| Molecular Formula | C22H25Cl2N7O2S |
| Molecular Weight | 522.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Dasatinib Impurity 6 (C22H25Cl2N7O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Dasatinib Impurity 6 (CAS CATO-C4X-16076) is a certified pharmaceutical impurity reference standard with the molecular formula C22H25Cl2N7O2S and a molecular weight of 522.45 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Dasatinib Impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H25Cl2N7O2S |
| Molecular Weight | 522.45 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Dasatinib Standards
- Dasatinib Impurity 64 (CAS 2468737-75-7)
- Dasatinib Impurity 65 (CAS 2468737-76-8)
- Dasatinib Impurity 66 (CAS 2468737-89-3)
- Dasatinib Impurity 7 (CAS CATO-C4X-16077)
- Dasatinib Impurity 8 (CAS CATO-C4X-16078)
- Dasatinib Impurity 30 (CAS 1417651-54-7)
- Dasatinib Impurity 77 (CAS CATO-C4X-160777)
- Dasatinib Impurity 48 (CAS CATO-C4X-160748)
Recommended Standards
- 1,4-Bis((4-(difluoromethoxy)phenyl)amino)anthracene-9,10-dione (CAS 62149-29-5)
- (E)-Ethyl 5-(benzyloxy)-6-bromo-1-methyl-2-(2-(phenylthio)vinyl)-1H-indole-3-carboxylate 1704066-47-6 (CAS 1704066-47-6)
- Ethyl 2-(2-((5-(4-bromophenyl)-1,3,4-oxadiazol-2-yl)thio)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 332161-19-0)
- 5,12-Bis(4-(trifluoromethyl)phenyl)-5,12-dihydroquinoxalino[2,3-b]quinoxaline (CAS 2361129-11-3)
- Iobitridol Impurity 23 (CAS CATO-C4X-317823)
- Amlodipine Impurity 56 (CAS 2418591-36-1)
- Moxifloxacin EP Impurity H 4-methylbenzenesulfonic acid (CAS CATO-C4X-107476)
- Tert-butyl methyl(4-(3-(trifluoromethyl)benzyl)piperidin-4-yl)carbamate (CAS 1983938-18-6)
- 1-(8-Propylquinolin-2-yl)ethanone (CAS 1245822-63-2)
- Paricalcitol lmpurity 42 (CAS 1186587-53-0)
- N-(1-((4-Methoxyphenyl)sulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)acetamide (CAS 946336-17-0)
- 1,2,3,4-Tetrahydro-5-isoquinolinol (CAS 102877-50-9)
- 3-(1-(2,4-Dimethylphenyl)-3-methyl-5-oxo-4,5-dihydro-1h-pyrazol-4-yl)propanoic acid (CAS 1204298-02-1)
- Myosin Kinase Inhibiting Peptide (CAS 119386-39-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com