N-(2-Chlorophenyl)-2,2-diphenylacetamide CAS 349644-54-8

Purity 97%+In StockPharmaceutical Standards
CAS No.349644-54-8
Molecular FormulaC20H16ClNO
Molecular Weight321.80 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(2-Chlorophenyl)-2,2-diphenylacetamide CAS 349644-54-8 chemical structure

Description

The occurrence of N-(2-Chlorophenyl)-2,2-diphenylacetamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies N-(2-Chlorophenyl)-2,2-diphenylacetamide (CAS 349644-54-8), a certified reference material (molecular formula C20H16ClNO, MW 321.80 g/mol) for analytical method development and quality control.

The molecular framework of N-(2-Chlorophenyl)-2,2-diphenylacetamide (C20H16ClNO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures N-(2-Chlorophenyl)-2,2-diphenylacetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC20H16ClNO
Molecular Weight321.80 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms1

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