Ethyl 4-amino-5-chloro-2-methoxybenzoate CAS 35019-78-4
| CAS No. | 35019-78-4 |
| Molecular Formula | C10H12ClNO3 |
| Molecular Weight | 229.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 229.66 g/mol gives Ethyl 4-amino-5-chloro-2-methoxybenzoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Ethyl 4-amino-5-chloro-2-methoxybenzoate (CAS 35019-78-4), a certified reference material (molecular formula C10H12ClNO3, MW 229.66 g/mol) for analytical method development and quality control.
Structurally, Ethyl 4-amino-5-chloro-2-methoxybenzoate (C10H12ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 229.66 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 4-amino-5-chloro-2-methoxybenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12ClNO3 |
| Molecular Weight | 229.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Ethyl 2-amino-4-chloro-5-methoxybenzoate (CAS 108494-83-3)
- 2-Amino-1-(8-chloro-2,3-dihydro-1,4-benzodioxin-6-yl)ethan-1-ol (CAS 1094248-62-0)
- Methyl 4-amino-5-chloro-2-ethoxybenzoate (CAS 112914-03-1)
- Methyl 5-amino-2-chloro-4-ethoxybenzoate (CAS 1143026-57-6)
- Ethyl 2-amino-4-chloro-3-methoxybenzoate (CAS 1247605-97-5)
- 3-Amino-3-(7-chlorobenzo[d][1,3]dioxol-5-yl)propan-1-ol (CAS 1250089-97-4)
- Ethyl 2-amino-3-chloro-5-methoxybenzoate (CAS 1251227-12-9)
- 3-Amino-3-(3-chloro-5-methoxyphenyl)propanoic acid (CAS 1273674-48-8)
Recommended Standards
- Ethyl 3-chloro-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-2-carboxylate (CAS 903130-23-4)
- ethyl 4-chloro-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylate (CAS 853109-70-3)
- Ethyl 2-chloro-4-(dimethylamino)pyrimidine-5-carboxylate (CAS 823796-35-6)
- Ethyl 4-chloro-2-(dimethylamino)pyrimidine-5-carboxylate (CAS 54127-87-6)
- N-(3-Amino-2,4-dichlorobenzyl)pivalamide (CAS 1360623-99-9)
- 1-Cyclohexyl-2-(4-methoxyphenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 496013-12-8)
- Ethyl 4-(p-tolylcarbamothioyl)piperazine-1-carboxylate (CAS 431913-97-2)
- 4-(4-Chlorophenyl)cyclohexanecarboxylic Acid (CAS 95233-37-7)
- 2-methyl-1H,4H-pyrazolo[1,5-a][1,3,5]triazin-4-one (CAS 55457-17-5)
- 2-(4-(Methoxymethyl)piperidin-1-yl)pyridin-3-amine (CAS 1339684-21-7)
- (2-Methyl-1H-imidazo[4,5-c]pyridin-4-yl)methanamine (CAS 933704-95-1)
- 1,3-Benzenedisulfonic acid, 4-[2-[5-(aminocarbonyl)-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridinyl]diazenyl]-6-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]-, sodium salt (CAS 70865-29-1)
- 2-Mercapto-3-phenyl-5-[2-(trifluoromethyl)benzylidene]-3,5-dihydro-4H-imidazol-4-one (CAS 905528-52-1)
- TAT 14 Peptide (Nrf2 Activator III) (CAS 1362661-34-4)
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