Terbutaline Impurity 60 CAS 35086-59-0
| CAS No. | 35086-59-0 |
| Molecular Formula | C12H12O5 |
| Molecular Weight | 236.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Terbutaline Impurity 60 (CAS 35086-59-0, C12H12O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Terbutaline Impurity 60 (C12H12O5) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C12H12O5 |
| Molecular Weight | 236.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
Related Terbutaline Standards
- Terbutaline impurity 124 (CAS CATO-C4X-1183124)
- Terbutaline impurity 125 (CAS CATO-C4X-1183125)
- Terbutaline impurity 129 (CAS CATO-C4X-1183129)
- Terbutaline EP impurity B (CAS 94120-05-5)
- Terbutaline impound 95 (CAS CATO-C4X-118395)
- Terbutaline-d9 (CAS 1189658-09-0)
- Terbutaline Impurity 32 (CAS CATO-C4X-118332)
- Terbutaline impurity 87 (CAS CATO-C4X-118387)
Recommended Standards
- N-Formyl Kynurenine (CAS 1022-31-7)
- Tryptophan Impurity 16 (CAS CATO-C4X-137316)
- Tryptophan EP Impurity B (Mixture of Diastereomers) (CAS 184955-21-3)
- Erlotinib Impurity 86 (CAS CATO-C4X-106986)
- Etrasimod Impurity 67 (CAS CATO-C4X-321467)
- Carfilzomib Impurity 40 (CAS CATO-C4X-102240)
- Olmesartan Impurity 80 (CAS 752179-89-8)
- Dapagliflozin 4-Bromo Analog (CAS 1807632-95-6)
- Malic Acid Impurity 7 (CAS CATO-C4X-25097)
- 4-(2-(1-Ethyl-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-6-yl)vinyl)-1-(2-hydroxyethyl)pyridin-1-ium chloride (CAS 80162-59-0)
- Ym 750 (CAS 138046-43-2)
- 2-((2-Amino-6-chloropyrimidin-4-yl)amino)benzoic acid (CAS 18160-09-3)
- 3-((3-Methylbenzyl)thio)-4-phenyl-5-(1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl)-4H-1,2,4-triazole (CAS 956625-77-7)
- Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 2022956-56-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com