3-(6-Chloro-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-propionic acid CAS 351003-03-7
| CAS No. | 351003-03-7 |
| Molecular Formula | C11H10ClNO4 |
| Molecular Weight | 255.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(6-Chloro-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-propionic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(6-Chloro-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-propionic acid (CAS 351003-03-7) is a high-purity analytical reference standard with the molecular formula C11H10ClNO4 and a molecular weight of 255.65 g/mol.
Structurally, 3-(6-Chloro-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-propionic acid (C11H10ClNO4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 255.65 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(6-Chloro-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-propionic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10ClNO4 |
| Molecular Weight | 255.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- Methyl 2-(6-chloro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)acetate (CAS 104662-84-2)
- 4-(3-Chloro-2-fluorophenoxy)-3-fluoroaniline (CAS 1206593-32-9)
- (7-Chloro-5-oxo-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl)acetic acid (CAS 1243086-72-7)
- Methyl 6-chloro-4-methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxylate (CAS 141761-83-3)
- 2-(7-Chloro-2-methyl-3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl)acetic acid (CAS 1510338-58-5)
- (R)-2-(3-Chloro-2-hydroxypropoxy)isoindoline-1,3-dione (CAS 338786-76-8)
- (S)-2-(3-Chloro-2-hydroxypropoxy)isoindoline-1,3-dione (CAS 272447-40-2)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thiourea (CAS 321430-48-2)
Recommended Standards
- 2-Oxotetrahydrofuran-3-yl 3-amino-4-chlorobenzoate (CAS 454241-27-1)
- 3-Chloro-2-(3,4-difluorophenoxy)aniline (CAS 946682-44-6)
- 2-(6-Chloro-2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-4-yl)acetic acid (CAS 942863-51-6)
- 3-Chloro-4-(2,4-difluorophenoxy)aniline (CAS 946662-64-2)
- 6-Bromo-3-isopropoxy-2-methylpyridine (CAS 1392466-94-2)
- 5-Amino-2-(hydroxymethyl)pyridine (CAS 873651-92-4)
- 4-Bromo-7-(trifluoromethyl)-1H-indole (CAS 1360959-14-3)
- 6-Bromo-2-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one (CAS 72472-43-6)
- 3639-21-2 2-Ethyl-2-hydroxy-butyric acid 2-ethyl-2-hydroxybutanoic acid CHEBI:165404 (CAS 3639-21-2)
- 3-[3-(trifluoromethyl)phenyl]prop-2-yn-1-amine hydrochloride (CAS 1052550-23-8)
- 5-Methyl-1,3-benzoxazole-2-carbothioamide (CAS 33653-01-9)
- Cholic Acid Impurity 81 (CAS CATO-C4X-116081)
- 2-(3-(2,6-Difluorophenyl)-1,2,4-oxadiazol-5-yl)aniline (CAS 1708250-77-4)
- Semaglutide Impurity 187 (CAS CATO-C4X-2226187)
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