2-(4-(Methylthio)phenyl)quinoline-4-carboxylic acid CAS 351065-46-8
| CAS No. | 351065-46-8 |
| Molecular Formula | C17H13NO2S |
| Molecular Weight | 295.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(4-(Methylthio)phenyl)quinoline-4-carboxylic acid (CAS 351065-46-8), molecular formula C17H13NO2S and molecular weight 295.36 g/mol, is a CATO reference standard with documented purity and traceability.
2-(4-(Methylthio)phenyl)quinoline-4-carboxylic acid (C17H13NO2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H13NO2S |
| Molecular Weight | 295.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methylthio Standards
- 3-(Methylthio)-2-phenylquinoline-4-carboxylic acid (CAS 400079-66-5)
- 2-((4-(Methylthio)phenyl)amino)pyridine-3-sulfonamide (CAS 1340859-21-3)
- 2-(Methylthio)-1-(o-tolyl)-5-(p-tolyl)-1H-imidazole (CAS 1207045-94-0)
- 4-Ethyl-3-(methylthio)-1,5-diphenyl-1H-pyrazole (CAS 871110-28-0)
- 3-(Methylthio)propanamide (CAS 22551-25-3)
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- 2-(Methylthio)-3,5-diphenylpyrimidin-4(3H)-one (CAS 133858-35-2)
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Recommended Standards
- 2-(4-(Benzyloxy)phenyl)thiazole-4-carbaldehyde (CAS 885278-93-3)
- 2-(5-(Pyrrolidin-1-ylsulfonyl)-1H-benzo[d][1,2,3]triazol-1-yl)ethan-1-amine (CAS 951523-69-6)
- 2-(3-(Benzyloxy)phenyl)thiazole-4-carbaldehyde (CAS 885278-72-8)
- 2-(Benzenesulfonyl)-5-phenylpenta-2,4-dienenitrile (CAS 861070-30-6)
- 2-Aminopyrimidin-4-ol (CAS 100643-25-2)
- 4-Methyl-2-(pyrrolidin-2-ylmethoxy)pyrimidine (CAS 1339656-33-5)
- 1-Boc-3-(4-nitrophenyl)azetidine (CAS 883901-62-0)
- Hydroxy Bosentan-d6 (CAS 1246817-57-1)
- 1-(difluoromethoxy)-2-ethynyl-cyclohexane (CAS 2306264-87-7)
- DiAzKs (CAS 1253643-88-7)
- L-Lysyl-L-methionine--formic acid (1/1) (CAS 103404-63-3)
- (3-Methoxyphenyl)methyl chloroformate (CAS 81228-89-9)
- (5-Methyl-6-(piperidin-1-yl)pyridin-3-yl)(phenyl)methanone (CAS 1355182-20-5)
- (Gly1,Ser3·22,Gln?·3?,Thr?,Arg1?,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) (CAS 313988-89-5)
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