2-(Methylthio)-3,5-diphenylpyrimidin-4(3H)-one CAS 133858-35-2
| CAS No. | 133858-35-2 |
| Molecular Formula | C17H14N2OS |
| Molecular Weight | 294.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-(Methylthio)-3,5-diphenylpyrimidin-4(3H)-one (CAS 133858-35-2) is a high-purity analytical reference standard with the molecular formula C17H14N2OS and a molecular weight of 294.37 g/mol.
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, 2-(Methylthio)-3,5-diphenylpyrimidin-4(3H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 294.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C17H14N2OS |
| Molecular Weight | 294.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methylthio Standards
- 2-(Methylthio)-3,6-diphenylpyrimidin-4(3H)-one (CAS 89069-41-0)
- 3-(4-(Methylthio)phenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 618098-86-5)
- N1-(2-(Methylthio)phenyl)-N2-((tetrahydrofuran-2-yl)methyl)oxalamide (CAS 941962-92-1)
- 2-(6-(Methylthio)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethan-1-amine (CAS 1105197-45-2)
- 2-(Methylthio)-1-(o-tolyl)-5-(p-tolyl)-1H-imidazole (CAS 1207045-94-0)
- 4-(Methylthio)-2-oxo-6-(quinolin-2-yl)-2H-pyran-3-carbonitrile (CAS 61380-94-7)
- 4-Ethyl-3-(methylthio)-1,5-diphenyl-1H-pyrazole (CAS 871110-28-0)
- 2-(4-(Methylthio)phenyl)quinoline-4-carboxylic acid (CAS 351065-46-8)
Recommended Standards
- 2-Phenyl-3-sulfanylidene-1H,2H,3H,5H,10H,10aH-imidazo[1,5-b]isoquinolin-1-one (CAS 133211-51-5)
- 1-(Furan-3-ylmethyl)-1-(2-methoxyethyl)-3-(thiophen-2-ylmethyl)urea (CAS 1421442-41-2)
- (5E)-2-Mercapto-5-(4-methylbenzylidene)-3-phenyl-3,5-dihydro-4H-imidazol-4-one 13109-87-0 (CAS 13109-87-0)
- Ethyl (2-(2-(3,5-dimethyl-1H-pyrazol-1-yl)thiazol-4-yl)ethyl)carbamate (CAS 1421498-83-0)
- 2-(2-Chlorophenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160254-31-8)
- triazolo[1,5-a]pyridine (CAS 274-59-9)
- (2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)(1-methyl-1H-pyrrol-2-yl)methanol (CAS 1443306-93-1)
- L-Serine-3,3-d2 (CAS 95034-57-4)
- 3-(2-nitrovinyl)thiophene (CAS 28783-31-5)
- 5-(2-Methoxyphenyl)pyrimidin-4-amine (CAS 856974-25-9)
- Canagliflozin Impurity 103 (CAS CATO-C4X-1123103)
- 2-Amino-5-(4-chlorophenyl)thiazole-4-carbohydrazide (CAS 886361-54-2)
- 5-Cyano-4-cyclopropoxynicotinic acid (CAS 1243451-35-5)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
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