2-(2-Bromobenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one CAS 351443-06-6
| CAS No. | 351443-06-6 |
| Molecular Formula | C16H9BrN2OS |
| Molecular Weight | 357.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(2-Bromobenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(2-Bromobenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one (CAS 351443-06-6), molecular formula C16H9BrN2OS and molecular weight 357.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(2-Bromobenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one (C16H9BrN2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(2-Bromobenzylidene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H9BrN2OS |
| Molecular Weight | 357.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Bromobenzylidene Standards
- (5E)-5-(3-Bromobenzylidene)-2-mercapto-3-phenyl-3,5-dihydro-4H-imidazol-4-one 301343-53-3 (CAS 301343-53-3)
- (5E)-5-(4-Bromobenzylidene)-2-mercapto-3-phenyl-3,5-dihydro-4H-imidazol-4-one 423741-80-4 (CAS 423741-80-4)
- (Z)-2-(4-Bromobenzylidene)-4,6-dimethoxybenzofuran-3(2H)-one (CAS 350982-89-7)
- N'-(3-Bromobenzylidene)-4-methylbenzenesulfonohydrazide (CAS 158918-48-0)
- N'-(2-bromobenzylidene)-4-methylbenzenesulfonohydrazide (CAS 158918-49-1)
- N'-(4-bromobenzylidene)-4-methylbenzenesulfonohydrazide (CAS 19350-68-6)
- N'-(4-Bromobenzylidene)-2-(4-nitrophenyl)acetohydrazide (CAS 328556-36-1)
- 2-(2-Bromobenzylidene)-6-methyl-2H-thiazolo[3,2-b][1,2,4]triazine-3,7-dione (CAS 463367-02-4)
Recommended Standards
- 1-(1-(4-Bromophenyl)-1H-pyrrol-3-yl)-N-(4-fluorobenzyl)methanimine (CAS 551930-64-4)
- 2-(2-Bromophenyl)-4H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-4-one (CAS 2248255-22-1)
- (E)-2-(((5-bromothiophen-2-yl)methylene)amino)-5-phenylfuran-3-carbonitrile (CAS 478033-42-0)
- 2-(4-Bromophenyl)-4H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-4-one (CAS 374097-37-7)
- (S)-2-Amino-1-((R)-3-(benzyl(isopropyl)amino)pyrrolidin-1-yl)-3-methylbutan-1-one (CAS 1401665-50-6)
- 9-Benzyl-6-chloro-N-phenyl-9H-purin-2-amine (CAS 666823-27-4)
- 5-(4-Chlorophenyl)-3,4-dihydro-2H-pyrrole (CAS 22217-78-3)
- 4-(piperazin-1-yl)pyridine-2-carboxylic acid dihydrochloride (CAS 1955522-65-2)
- Diethyl 2-(4-bromophenyl)succinate (CAS 1255783-31-3)
- Nilotinib Impurity 39 (CAS 2925306-68-7)
- Imastaxime Impurity 2 (CAS CATO-C4X-31352)
- 4-Cyclopropoxy-1-iodo-2-nitrobenzene (CAS 1243350-08-4)
- 5-(3-Methylphenyl)-1-pentene (CAS 51125-15-6)
- Peptide YY (canine, mouse, porcine, rat) trifluoroacetate salt (CAS 81858-94-8)
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