5-Amino-4-chloro-1H-pyrazole-3-carboxylic acid CAS 351990-69-7
| CAS No. | 351990-69-7 |
| Molecular Formula | C4H4ClN3O2 |
| Molecular Weight | 161.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 161.55 g/mol gives 5-Amino-4-chloro-1H-pyrazole-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Amino-4-chloro-1H-pyrazole-3-carboxylic acid (CAS 351990-69-7) is a high-purity analytical reference standard with the molecular formula C4H4ClN3O2 and a molecular weight of 161.55 g/mol.
5-Amino-4-chloro-1H-pyrazole-3-carboxylic acid (C4H4ClN3O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Amino-4-chloro-1H-pyrazole-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H4ClN3O2 |
| Molecular Weight | 161.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
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Recommended Standards
- 5-(Chloromethyl)-1,2,4-oxadiazole-3-carboxamide (CAS 34879-29-3)
- 5-Chloro-1H-[1,2,3]triazole-4-carboxylic acidmethyl ester (CAS 88474-33-3)
- 4-Chloro-5-methyl-3-nitro-1H-pyrazole (CAS 512810-26-3)
- 5-Chloro-1H-1,2,4-triazole-3-carbohydrazide (CAS 199292-15-4)
- 2-((4-Chlorobenzyl)(isopropyl)amino)acetic acid (CAS 1181654-06-7)
- 2,4,5,6-tetrahydroindazol-7-one (CAS 165686-41-9)
- 3-(1-Isopropyl-1H-pyrazol-4-yl)propanoic acid (CAS 1007485-76-8)
- Methyl 5-(Benzo[d][1,3]dioxol-5-yl)isoxazole-3-carboxylate (CAS 668971-48-0)
- 2-Amino-N-methyl-N-(1-(pyridin-2-yl)ethyl)acetamide (CAS 1353978-47-8)
- 2,3-Dimethyl-3H-imidazo[4,5-b]pyridine-6-carboxylic acid (CAS 927801-46-5)
- tert-Butyl (2S,5R)-2,5-dibenzylpiperazine-1-carboxylate (CAS 1224977-21-2)
- 5,5'-Diallyl-3-(4-allylphenoxy)-[1,1'-biphenyl]-2,2'-diol (CAS 139726-30-0)
- 2-Chloro-N-[5-(4-nitrobenzenesulfonyl)-1,3-thiazol-2-yl]acetamide (CAS 379255-52-4)
- Des-Ala18-Tirzepatide (CAS CATO-CPTD788955)
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