4-(4-Chlorophenoxy)phenylsulfonyl fluoride CAS 352209-77-9
| CAS No. | 352209-77-9 |
| Molecular Formula | C12H8ClFO3S |
| Molecular Weight | 286.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 286.71 g/mol gives 4-(4-Chlorophenoxy)phenylsulfonyl fluoride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-(4-Chlorophenoxy)phenylsulfonyl fluoride (CAS 352209-77-9), a certified reference material (molecular formula C12H8ClFO3S, MW 286.71 g/mol) for analytical method development and quality control.
The molecular framework of 4-(4-Chlorophenoxy)phenylsulfonyl fluoride (C12H8ClFO3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(4-Chlorophenoxy)phenylsulfonyl fluoride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8ClFO3S |
| Molecular Weight | 286.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Chlorophenoxy Standards
- 1-(((4-Chlorophenoxy)carbonyl)oxy)ethyl isobutyrate (CAS 1622940-14-0)
- 2-((4-Chlorophenoxy)methyl)-5-phenyl-1,3,4-oxadiazole (CAS 325804-04-4)
- 4-{3-[(3-chlorophenoxy)methyl]-1H-1,2,4-triazol-5-yl}pyridine (CAS 477852-70-3)
- 2-(4-Chlorophenoxy)-1-(5-chlorothiophen-2-yl)ethan-1-one (CAS 778620-19-2)
- 2-(2-Chlorophenoxy)-5-(trifluoromethyl)aniline (CAS 946727-99-7)
- 2-(3-Chlorophenoxy)-5-(trifluoromethyl)aniline (CAS 946773-26-8)
- 4-(2-Chlorophenoxy)-2-(trifluoromethyl)aniline (CAS 946698-00-6)
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Recommended Standards
- 4-(3-Fluorophenoxy)benzene-1-sulfonyl chloride (CAS 815576-23-9)
- 4-Amino-3-((2-chloro-6-fluorobenzyl)thio)-1,2,4-triazin-5(4H)-one (CAS 869068-64-4)
- 4-((4-Chlorophenyl)amino)-3-((2-hydroxyethyl)amino)-4-oxobutanoic acid (CAS 2096495-92-8)
- 5-(2-Chloro-4-fluorophenoxymethyl)thiophene-2-carboxylic acid (CAS 934127-20-5)
- CYSTEINE PROTEASE INHIBITOR HCL (CAS 2197053-49-7)
- Tert-butyl (6-oxa-2-azaspiro[3.4]Octan-8-yl)carbamate (CAS 2306265-38-1)
- Ethyl 3-formylisonicotinate (CAS 21908-13-4)
- 2-(1H-Pyrazol-1-yl)ethanesulfonyl chloride (CAS 1196146-43-6)
- Tert-butyl ((5-(hydroxymethyl)bicyclo[3.2.1]Octan-1-yl)methyl)carbamate (CAS 2197714-93-3)
- 13-Docosenoic acid, sodium salt (CAS 14488-85-8)
- 3-Methyl-3-(phenylmethoxy)butanoic Acid (CAS 96556-32-0)
- 1-Bromo-6-(trifluoromethyl)isoquinoline (CAS 1196152-93-8)
- Ethyl(1s,3s)-3-aminocyclohexanecarboxylate (CAS 1810774-46-9)
- Semaglutide impurity 77 (CAS CATO-C4X-222677)
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