4-[5-Chloro-2-nitro-4-(trifluoromethyl)phenyl]morpholine CAS 35289-26-0
| CAS No. | 35289-26-0 |
| Molecular Formula | C11H10ClF3N2O3 |
| Molecular Weight | 310.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-[5-Chloro-2-nitro-4-(trifluoromethyl)phenyl]morpholine (C11H10ClF3N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-[5-Chloro-2-nitro-4-(trifluoromethyl)phenyl]morpholine (CAS 35289-26-0), molecular formula C11H10ClF3N2O3 and molecular weight 310.66 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-[5-Chloro-2-nitro-4-(trifluoromethyl)phenyl]morpholine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10ClF3N2O3 |
| Molecular Weight | 310.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 2-(7-Chloro-1,8-naphthyridin-2-yl)isoindoline-1,3-dione (CAS 55112-40-8)
- 4-((2,5-Difluorophenyl)amino)-4-oxobutanoic acid (CAS 503425-60-3)
- (3aS,4S,6R,6aR)-6-(6-Chloro-9H-purin-9-yl)-N-ethyl-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carboxamide (CAS 103201-21-4)
- 5-Methyl-3H-1,2,4-triazole-3-thione (CAS 5803-95-2)
- 7-(Cbz-amino)heptanoic Acid (CAS 23434-37-9)
- tert-Butyl 5-bromo-3,4-dihydro-2,6-naphthyridine-2(1H)-carboxylate (CAS 1393552-99-2)
- 1566571-78-5 25H-NBOMe imine analog (CAS 1566571-78-5)
- D-Phe6-Tirzepatide (CAS CATO-CPTD788925)
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