1-(4-Nitrophenyl)-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole CAS 353457-70-2
| CAS No. | 353457-70-2 |
| Molecular Formula | C14H12F3N3O2 |
| Molecular Weight | 311.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(4-Nitrophenyl)-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(4-Nitrophenyl)-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole (CAS 353457-70-2), molecular formula C14H12F3N3O2 and molecular weight 311.26 g/mol, is a CATO reference standard with documented purity and traceability.
1-(4-Nitrophenyl)-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole (C14H12F3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(4-Nitrophenyl)-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H12F3N3O2 |
| Molecular Weight | 311.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Nitrophenyl Standards
- 1-(2-Nitrophenyl)-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazole (CAS 1018143-05-9)
- 2-(5-(2-Nitrophenyl)-1,3,4-oxadiazol-2-yl)benzoic acid (CAS 56894-42-9)
- 2-(5-(3-Nitrophenyl)-1,3,4-oxadiazol-2-yl)benzoic acid (CAS 56894-38-3)
- 2-(5-(4-Nitrophenyl)-1,3,4-oxadiazol-2-yl)benzoic acid (CAS 56894-71-4)
- 1-(3-Nitrophenyl)-5-phenyl-4,5-dihydro-1h-pyrazole-3-carboxylic acid (CAS 1264039-55-5)
- 1-(4-Nitrophenyl)-5-phenyl-4,5-dihydro-1h-pyrazole-3-carboxylic acid (CAS 1264043-25-5)
- 2-[(2E)-3-(3-Nitrophenyl)prop-2-enamido]benzamide (CAS 188544-09-4)
- 4-Methyl-7-[(4-nitrophenyl)methoxy]-2H-chromen-2-one (CAS 314741-99-6)
Recommended Standards
- (E)-2-methoxy-6-(((4-(trifluoromethoxy)phenyl)imino)methyl)phenol (CAS 303769-15-5)
- 2,2-Difluoro-2-(4-fluorophenoxy)-N-(4-methoxyphenyl)acetamide (CAS 338792-49-7)
- Ethyl 2-(phenylamino)-4-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 187035-92-3)
- 2-Bromo-1-(4-octylphenyl)ethanone (CAS 64068-76-4)
- 2-(2-(2,3-Difluorophenoxy)ethyl)-1,3-dioxolane (CAS 1443303-99-8)
- Octyl β-D-galactopyranoside (CAS 40427-75-6)
- 4-Methyl-2-(oxazol-5-yl)phenol (CAS 2379322-27-5)
- 3-[(4-fluorophenyl)-5-(2-bromoacetyl)]isoxazole (CAS 888723-43-1)
- 2,6-Difluoro-N-((5-(furan-2-carbonyl)thiophen-2-yl)methyl)benzenesulfonamide (CAS 1797964-33-0)
- n-((2,3-Dihydrobenzofuran-3-yl)methyl)-o-methylhydroxylamine (CAS 1516910-62-5)
- 3-((1-Hydroxybutan-2-yl)amino)thietane 1,1-dioxide (CAS 1871685-81-2)
- 4,5-Dichloro-2-iodopyrimidine (CAS 1805483-56-0)
- Ethyl 5-(pyridin-2-yl)-4,5-dihydrooxazole-4-carboxylate (CAS 1478691-54-1)
- D-Phe22-Tirzepatide (CAS CATO-CPTD788912)
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