2,2-Difluoro-2-(4-fluorophenoxy)-N-(4-methoxyphenyl)acetamide CAS 338792-49-7
| CAS No. | 338792-49-7 |
| Molecular Formula | C15H12F3NO3 |
| Molecular Weight | 311.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,2-Difluoro-2-(4-fluorophenoxy)-N-(4-methoxyphenyl)acetamide.
CATO supplies 2,2-Difluoro-2-(4-fluorophenoxy)-N-(4-methoxyphenyl)acetamide (CAS 338792-49-7), a certified reference material (molecular formula C15H12F3NO3, MW 311.26 g/mol) for analytical method development and quality control.
The molecular framework of 2,2-Difluoro-2-(4-fluorophenoxy)-N-(4-methoxyphenyl)acetamide (C15H12F3NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,2-Difluoro-2-(4-fluorophenoxy)-N-(4-methoxyphenyl)acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H12F3NO3 |
| Molecular Weight | 311.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- (R)-tert-butyl (4-(1H-imidazol-1-yl)-4-oxo-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate (CAS 1364122-90-6)
- 1-(6-Methylpyrimidin-4-yl)piperidin-3-ol (CAS 1249221-92-8)
- N-(piperidin-4-yl)-1-benzofuran-2-carboxamide hydrochloride (CAS 150515-80-3)
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- 1-((3,5-Dimethylpiperidin-1-yl)sulfonyl)piperazine (CAS 923684-29-1)
- n-{2-[4-(2-chloroacetyl)phenyl]ethyl}acetamide (CAS 63077-41-8)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com