3-Hydroxy-2-(naphtho[2,1-b]furan-2-yl)-4H-chromen-4-one CAS 353497-65-1

Purity 97%+In StockPharmaceutical Standards
CAS No.353497-65-1
Molecular FormulaC21H12O4
Molecular Weight328.32 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Hydroxy-2-(naphtho[2,1-b]furan-2-yl)-4H-chromen-4-one CAS 353497-65-1 chemical structure

Description

The occurrence of 3-Hydroxy-2-(naphtho[2,1-b]furan-2-yl)-4H-chromen-4-one is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3-Hydroxy-2-(naphtho[2,1-b]furan-2-yl)-4H-chromen-4-one (CAS 353497-65-1), molecular formula C21H12O4 and molecular weight 328.32 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-Hydroxy-2-(naphtho[2,1-b]furan-2-yl)-4H-chromen-4-one (C21H12O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-Hydroxy-2-(naphtho[2,1-b]furan-2-yl)-4H-chromen-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC21H12O4
Molecular Weight328.32 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)16.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025

Related Hydroxy Standards

Recommended Standards

Why CATO?