2-Chloro-2,2-difluoroacetamide CAS 354-28-9
| CAS No. | 354-28-9 |
| Molecular Formula | C2H2ClF2NO |
| Molecular Weight | 129.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 129.49 g/mol gives 2-Chloro-2,2-difluoroacetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloro-2,2-difluoroacetamide (CAS 354-28-9), molecular formula C2H2ClF2NO and molecular weight 129.49 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-Chloro-2,2-difluoroacetamide is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 129.49 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-2,2-difluoroacetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C2H2ClF2NO |
| Molecular Weight | 129.49 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-2-hydroxypyridine (CAS 13466-35-8)
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- 5-Chloro-1H-pyrrole-2-carbaldehyde (CAS 1757-28-4)
- 2-Chloro-5-hydroxypyridine (CAS 41288-96-4)
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Recommended Standards
- Bromochloromethane (CAS 74-97-5)
- 4-Chloropyridine<I>N</I>-oxide (CAS 1121-76-2)
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- 1,1,1-Trimethyl-N-2-propen-1-ylsilanamine (CAS 10519-97-8)
- 2-(Methoxymethyl)-4-(trifluoromethyl)pyrimidine-5-carboxylic acid (CAS 1216015-14-3)
- 1-Bromo-2-(4-ethylbenzyl)-4-iodobenzene (CAS 1006383-23-8)
- 2-((5-Amino-4-methyl-4h-1,2,4-triazol-3-yl)thio)acetic acid (CAS 1304471-02-0)
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- 1-Propenyl-3-methylimidazolium nitrate (CAS 649745-76-6)
- 4-(4-Aminophenoxy)benzene-1-sulfonamide (CAS 108016-36-0)
- (S)-N-(2-(3-aminopyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide (CAS 857650-90-9)
- (4,5,6,7-Tetrahydro-1H-benzimidazol-2-ylmethyl)amine dihydrochloride (CAS 1448125-97-0)
- 7-Bromo-2,4,8-trichloro-6-(trifluoromethyl)quinazoline (CAS 2823478-91-5)
- Smac-N7 Peptide (CAS 401913-57-3)
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