1-Chloro-N,N-dimethylmethanesulfonamide CAS 35427-68-0
| CAS No. | 35427-68-0 |
| Molecular Formula | C3H8ClNO2S |
| Molecular Weight | 157.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Chloro-N,N-dimethylmethanesulfonamide (CAS 35427-68-0) is a high-purity analytical reference standard with the molecular formula C3H8ClNO2S and a molecular weight of 157.62 g/mol.
The molecular framework of 1-Chloro-N,N-dimethylmethanesulfonamide (C3H8ClNO2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Chloro-N,N-dimethylmethanesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C3H8ClNO2S |
| Molecular Weight | 157.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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- 1-Ethyl-3-methylpyrimidine-2,4(1H,3H)-dione (CAS 62415-62-7)
- Des-Ile17-Tirzepatide (CAS CATO-CPTD788956)
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