4-(Pyrrolidine-1-carbonyl)benzenesulfonyl chloride CAS 354587-60-3
| CAS No. | 354587-60-3 |
| Molecular Formula | C11H12ClNO3S |
| Molecular Weight | 273.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Pyrrolidine-1-carbonyl)benzenesulfonyl chloride.
CATO supplies 4-(Pyrrolidine-1-carbonyl)benzenesulfonyl chloride (CAS 354587-60-3), a certified reference material (molecular formula C11H12ClNO3S, MW 273.74 g/mol) for analytical method development and quality control.
4-(Pyrrolidine-1-carbonyl)benzenesulfonyl chloride (C11H12ClNO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12ClNO3S |
| Molecular Weight | 273.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Pyrrolidine Standards
- 3-(Pyrrolidine-1-carbonyl)benzenesulfonyl chloride (CAS 1016723-95-7)
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- 2-Methyl-5-(pyrrolidine-1-sulfonyl)benzoic acid (CAS 353467-90-0)
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- [3-Methyl-5-(pyrrolidine-1-sulfonyl)phenyl]boronic acid (CAS 2377611-76-0)
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Recommended Standards
- 4-(2-Oxopiperidin-1-yl)benzenesulfonyl chloride (CAS 927999-47-1)
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- 4-(1,3-Benzothiazol-2-yl)benzoyl chloride (CAS 2182-79-8)
- 6-Chloro-2-propyl-1H-benzo[d]imidazole-5-sulfonamide (CAS 89725-06-4)
- 4-Bromo-2,6-dinitroaniline (CAS 62554-90-9)
- 3-(Tetrahydro-2h-pyran-4-yl)acrylic acid (CAS 1278963-15-7)
- 2-(1H-Benzo[d]imidazol-2-yl)-4,5-dihydrooxazole (CAS 14483-99-9)
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- (S)-2-(2,4-dichlorophenyl)-2-(methylamino)ethan-1-ol (CAS 1212914-36-7)
- Methyl 2-(((3-oxo-2,3-dihydro-1H-pyrazol-4-yl)methylene)amino)acetate (CAS 339107-24-3)
- Sivelestat Impurity 28 (CAS CATO-C4X-212328)
- Ethyl 7-amino-6-chloro-1,8-naphthyridine-3-carboxylate (CAS 2255313-83-6)
- N-(4-Carbamoylphenyl)-5-ethyl-11-oxo-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide (CAS 1574567-58-0)
- Tirzepatide Impurity 43 (CAS CATO-C4X-324043)
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