6-Chloro-2-isopropyl-1H-benzo[d]imidazole-5-sulfonamide CAS 89725-22-4

Purity 97%+In StockPharmaceutical Standards
CAS No.89725-22-4
Molecular FormulaC10H12ClN3O2S
Molecular Weight273.74 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Chloro-2-isopropyl-1H-benzo[d]imidazole-5-sulfonamide CAS 89725-22-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-2-isopropyl-1H-benzo[d]imidazole-5-sulfonamide.

CATO supplies 6-Chloro-2-isopropyl-1H-benzo[d]imidazole-5-sulfonamide (CAS 89725-22-4), a certified reference material (molecular formula C10H12ClN3O2S, MW 273.74 g/mol) for analytical method development and quality control.

6-Chloro-2-isopropyl-1H-benzo[d]imidazole-5-sulfonamide (C10H12ClN3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H12ClN3O2S
Molecular Weight273.74 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1982
Halogen ContentCl-containing
Nitrogen Atoms3
Sulfur Atoms1

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