2,6-di(2,2,2-Trifluoroethoxy)benzoic Acid CAS 35480-53-6

Purity 97%+In StockPharmaceutical Standards
CAS No.35480-53-6
Molecular FormulaC11H8F6O4
Molecular Weight318.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,6-di(2,2,2-Trifluoroethoxy)benzoic Acid CAS 35480-53-6 chemical structure

Description

As a certified reference material (CRM), 2,6-di(2,2,2-Trifluoroethoxy)benzoic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

CATO supplies 2,6-di(2,2,2-Trifluoroethoxy)benzoic Acid (CAS 35480-53-6), a certified reference material (molecular formula C11H8F6O4, MW 318.17 g/mol) for analytical method development and quality control.

The molecular framework of 2,6-di(2,2,2-Trifluoroethoxy)benzoic Acid (C11H8F6O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC11H8F6O4
Molecular Weight318.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1967
Halogen ContentF-containing

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