2-(3-Chloro-2-methylphenyl)-1,3-dioxoisoindoline-5-carboxylic acid CAS 356576-29-9
| CAS No. | 356576-29-9 |
| Molecular Formula | C16H10ClNO4 |
| Molecular Weight | 315.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(3-Chloro-2-methylphenyl)-1,3-dioxoisoindoline-5-carboxylic acid (C16H10ClNO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-(3-Chloro-2-methylphenyl)-1,3-dioxoisoindoline-5-carboxylic acid (CAS 356576-29-9), molecular formula C16H10ClNO4 and molecular weight 315.71 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(3-Chloro-2-methylphenyl)-1,3-dioxoisoindoline-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H10ClNO4 |
| Molecular Weight | 315.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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- 2-(3-Chloro-4-methylphenyl)-1,3-dioxoisoindoline-5-carboxylic acid (CAS 313260-37-6)
- 5-Chloro-2-(1,3-dihydro-1,3- dioxo-isoindol-2-yl)methylbenzoic acid (CAS 266341-87-1)
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Recommended Standards
- 1,6-Diamino-4-(3-chloro-4-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile (CAS 865660-13-5)
- 2-(4-Chlorobenzoyl)-3-methyl-5-nitro-1-benzofuran (CAS 400076-06-4)
- (2R,3R,4R,5R)-5-(6-Amino-8-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol (CAS 634207-55-9)
- 4-(2-Chlorophenyl)-2-(3-nitrophenyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 400076-67-7)
- N,N-Dimethyl-2-(perfluorophenoxy)ethanamine (CAS 2044704-44-9)
- Dicyclohexyldimethoxysilane (CAS 18551-20-7)
- 2-Bromo-6-methoxyquinazoline (CAS 1379334-93-6)
- N-methyl-N-(pyrrolidin-3-yl)pyrimidin-2-amine dihydrochloride (CAS 2379946-50-4)
- Empagliflozin Impurity 168 (CAS CATO-C4X-1065168)
- 1-(tert-butyl) 4-ethyl 1H-pyrazole-1,4-dicarboxylate (CAS 405103-00-6)
- 4,6-Dimethyl-2-piperidin-2-yl-pyrimidine dihydrochloride (CAS 1361113-55-4)
- Dimethyl 3-oxohexanedioate (CAS 5457-44-3)
- Ethyl 7-iodo-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 22200-48-2)
- Bradykinin-Like Neuropeptide (Aplysia californica) (H-1654.0001) (CAS 165174-60-7)
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