Homofolic Acid CAS 3566-25-4
| CAS No. | 3566-25-4 |
| Molecular Formula | C20H21N7O6 |
| Molecular Weight | 455.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 455.42 g/mol gives Homofolic Acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Homofolic Acid (CAS 3566-25-4), molecular formula C20H21N7O6 and molecular weight 455.42 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Homofolic Acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 455.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H21N7O6 |
| Molecular Weight | 455.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 7 |
Recommended Standards
- 2-((3-Cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridin-2-yl)thio)-N-(2,6-difluorophenyl)acetamide (CAS 496018-65-6)
- Isohomofolic Acid (CAS 24960-28-9)
- (2R,3R,4R,5R)-2-(6-Benzamido-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diyl diacetate (CAS 69293-36-3)
- Mal-amido-PEG3-C1-NHS ester (CAS 2101206-45-3)
- 6-Amino-5-((benzyl(methyl)amino)methyl)-1-methylpyrimidine-2,4(1H,3H)-dione (CAS 1797583-14-2)
- BI-224436, >98% (HPLC) (CAS 1155419-89-8)
- N-(Furan-2-ylmethyl)-3-(phenylthio)-N-(2-(thiophen-2-yl)ethyl)propanamide (CAS 1396673-90-7)
- Lenvatinib Impurity 33 (CAS 3964-52-1)
- N-Methyl-3-(trifluoromethyl)isoxazol-5-amine (CAS 110235-19-3)
- Methyl 4-(benzyloxy)-2-bromo-5-methoxybenzoate (CAS 139963-13-6)
- 3-(3-aminophenyl)-5-ethylimidazolidine-2,4-dione hydrochloride (CAS 1803562-16-4)
- 2-((4-Chlorobenzyl)(isopropyl)amino)acetic acid (CAS 1181654-06-7)
- Benzyl 5-fluoro-2,7-diazaspiro[3.5]Nonane-2-carboxylate (CAS 2306260-83-1)
- Semaglutide impurity 47 (CAS CATO-C4X-222647)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com