Varenicline Dioxo Impurity CAS 357424-07-8
| CAS No. | 357424-07-8 |
| Molecular Formula | C13H13N3O2 |
| Molecular Weight | 243.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Varenicline Dioxo Impurity (CAS 357424-07-8), a pharmacopoeial impurity reference standard (molecular formula C13H13N3O2, MW 243.26 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C13H13N3O2, Varenicline Dioxo Impurity contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 243.26 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Varenicline Dioxo Impurity under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H13N3O2 |
| Molecular Weight | 243.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related Varenicline Standards
- Varenicline Impurity 16 (CAS 1337563-47-9)
- Varenicline Impurity 58 (CAS CATO-C4X-196258)
- Varenicline Impurity 68 (CAS CATO-C4X-196268)
- Varenicline Impurity 25 (CAS CATO-C4X-196225)
- Varenicline Nitroso Impurity 36 (CAS CATO-C4X-196236)
- Varenicline Impurity 71 (CAS CATO-C4X-196271)
- Varenicline Impurity 13 (CAS 2755871-02-2)
- Varenicline Impurity 44 (CAS CATO-C4X-196244)
Recommended Standards
- 32864-08-7 (3,5-Dimethoxyphenyl)(pyridin-2-yl)methanone DTXSID90618517 (CAS 32864-08-7)
- 3-Amino-4-[(pyridin-3-ylmethyl)-amino]-benzoic acid 3450AE 436088-89-0 C13H13N3O2 (CAS 436088-89-0)
- 28123-73-1 AR-1K4860 n-{5-[(3-{[n5-(diaminomethylidene)ornithyl]amino}propyl)amino]pentyl}-n2-[(4-hydroxy-1h-indol-3-yl)acetyl]-n6-methyllysinamide (CAS 28123-73-1)
- 52119-38-7 Ethyl 3-nitrobenzoylacetate ethyl 3-(3-nitrophenyl)-3-oxopropanoate (CAS 52119-38-7)
- Pitavastatin Impurity 104 (CAS CATO-C4X-1037104)
- Isavuconazole Impurity 138 (CAS 2962831-00-9)
- Relugolix Impurity 58 (CAS CATO-C4X-242958)
- (5E)-2-Mercapto-5-(mesitylmethylene)-1,3-thiazol-4(5H)-one 153567-97-6 4779AD C13H13NOS2 (CAS 153567-97-6)
- 3-(4-Aminophenoxy)propanamide (CAS 121489-79-0)
- tert-Butyl 3-(chloromethyl)indoline-1-carboxylate (CAS 454674-65-8)
- 7-Deaza-2',3'-dideoxyadenosine (CAS 40627-30-3)
- 3-Phenanthrol-d9 (Major) (CAS 922510-20-1)
- 4-(Boc-amino)-1-pentanol (CAS 179412-96-5)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com