Sildenafil Impurity N58 CAS 358388-58-6
| CAS No. | 358388-58-6 |
| Molecular Formula | C19H21BrN4O3 |
| Molecular Weight | 433.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Sildenafil Impurity N58.
CATO supplies Sildenafil Impurity N58 (CAS 358388-58-6), a certified reference material (molecular formula C19H21BrN4O3, MW 433.30 g/mol) for analytical method development and quality control.
Sildenafil Impurity N58 (C19H21BrN4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Sildenafil Impurity N58 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H21BrN4O3 |
| Molecular Weight | 433.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Sildenafil Standards
- Sildenafil Impurity 281 (CAS CATO-C4X-1128281)
- Sildenafil Impurity 81 (CAS 2640792-65-8)
- Sildenafil Impurity 94 (CAS CATO-C4X-112894)
- Sildenafil Impurity 280 (CAS CATO-C4X-1128280)
- Sildenafil Impurity 95 (CAS CATO-C4X-112895)
- Sildenafil Impurity 295 (CAS CATO-C4X-1128295)
- Sildenafil Impurity 256 (CAS 1027192-9-2)
- Sildenafil Impurity 255 (CAS CATO-C4X-1128255)
Recommended Standards
- N-(4-bromophenyl)-2-(4-methoxyphenyl)quinoline-4-carboxamide (CAS 312321-04-3)
- Finerenone Impurity 258 (CAS 2953382-13-1)
- N-(4-bromo-3-methylphenyl)-2-(4-(4-nitrophenyl)piperazin-1-yl)acetamide (CAS 882080-37-7)
- (E)-[(2,6-Dichlorophenyl)methoxy]({[3-nitro-4-(phenylsulfanyl)phenyl]methylidene})amine (CAS 477852-26-9)
- 4-Bromo-N-cyclopropyl-1H-pyrazole-3-carboxamide (CAS 942693-91-6)
- 1,4-Dichlorocyclohexane (CAS 19398-57-3)
- Ethyl 1-(4-methoxyphenyl)-5-methyl-1H-pyrazole-3-carboxylate (CAS 126068-76-6)
- 1-(4-Cyclopentyl-4H-1,2,4-triazol-3-yl)ethanamine dihydrochloride (CAS 1269054-36-5)
- 5-Aminopyridine-3-carbothioamide (CAS 1355610-88-6)
- 3-(3-Methylthiophen-2-yl)benzene-1-sulfonyl chloride (CAS 1341979-62-1)
- Ethyl 5-(chloromethyl)-2,6-dimethylnicotinate (CAS 77825-10-6)
- 3-((2,5-Dichlorophenyl)sulfinyl)propanoic acid (CAS 1249655-47-7)
- 4-Chloro-N-(2-((2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)amino)phenyl)benzenesulfonamide (CAS 338772-81-9)
- Pancreatic Polypeptide (rat) (CAS 90419-12-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com