Ibuprofen EP Impurity B CAS 3585-49-7
| CAS No. | 3585-49-7 |
| Molecular Formula | C13H18O2 |
| Molecular Weight | 206.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Ibuprofen EP Impurity B (CAS 3585-49-7), a pharmacopoeial impurity reference standard (molecular formula C13H18O2, MW 206.28 g/mol) used for the identification and quantification of trace impurities in APIs.
Ibuprofen EP Impurity B (C13H18O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H18O2 |
| Molecular Weight | 206.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >90% |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Ibuprofen Standards
- (S)-Ibuprofen EP Impurity B (CAS 404354-76-3)
- Ibuprofen (CAS 15687-27-1)
- Ibuprofen EP Impurity A (CAS 66622-47-7)
- Ibuprofen Impurity 145 (CAS 69363-33-3)
- Ibuprofen EP Impurity A (CAS CATO-C4X-1082147)
- Ibuprofen EP Impurity O (CAS 64451-76-9)
- Ibuprofen Impurity 151 (CAS CATO-C4X-1082151)
- Ibuprofen Impurity 54 (CAS 158264-26-7)
Recommended Standards
- Ibuprofen EP Impurity F (CAS 65322-85-2)
- Ibuprofen Impurity 78 (CAS 51146-56-6)
- Ibuprofen Impurity 79 (CAS 51146-57-7)
- Dexmedetomidine Impurity 45 (CAS CATO-C4X-123045)
- Difelikefalin Impurity 34 (CAS CATO-C4X-304134)
- Mirabegron Impurity 139 (CAS 1330277-46-7)
- Avibactam impurity 93 (CAS CATO-C4X-134893)
- N-(adamantan-1-yl)-6-chloropyrimidin-4-amine (CAS 1242240-99-8)
- (4-Aminophenyl)(2-methylmorpholino)methanone (CAS 926257-59-2)
- N-((5-(Hydroxy(thiophen-3-yl)methyl)thiophen-2-yl)methyl)thiophene-2-sulfonamide (CAS 1798024-24-4)
- n-(Cyclopropylmethyl)-2-fluoro-5-methylaniline (CAS 1154386-16-9)
- 2-(4-Iodo-1h-pyrazol-1-yl)-1-morpholinoethan-1-one (CAS 1436205-29-6)
- 5-Amino-2,3-dihydro-1,3,4-thiadiazol-2-one (CAS 33901-30-3)
- RGD-targeted Proapoptotic Peptide trifluoroacetate salt (CAS 2243207-09-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com