(S)-Ibuprofen EP Impurity B CAS 404354-76-3
| CAS No. | 404354-76-3 |
| Molecular Formula | C13H18O2 |
| Molecular Weight | 206.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies (S)-Ibuprofen EP Impurity B (CAS 404354-76-3), a pharmacopoeial impurity reference standard (molecular formula C13H18O2, MW 206.28 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, (S)-Ibuprofen EP Impurity B (C13H18O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 206.28 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), (S)-Ibuprofen EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H18O2 |
| Molecular Weight | 206.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
Related S Standards
- Ibuprofen (CAS 15687-27-1)
- Ibuprofen EP Impurity A (CAS 66622-47-7)
- Ibuprofen Impurity 145 (CAS 69363-33-3)
- Ibuprofen EP Impurity A (CAS CATO-C4X-1082147)
- Ibuprofen EP Impurity O (CAS 64451-76-9)
- Ibuprofen Impurity 151 (CAS CATO-C4X-1082151)
- Ibuprofen EP Impurity B (CAS 3585-49-7)
- Ibuprofen Impurity 54 (CAS 158264-26-7)
Recommended Standards
- (2R,4R)-4-Benzyl-2-ethoxytetrahydrofuran (CAS 210561-08-3)
- (2S)-2-[[4-(1,1-Dimethylethyl)phenoxy]methyl]oxirane (CAS 250778-94-0)
- (2R)-4-(Phenylmethyl)-2-morpholinemethanamine (CAS 214273-17-3)
- (3,3-Diethoxyprop-1-en-1-yl)benzene (CAS 7148-78-9)
- Dipyridamole EP Impurity C (CAS 54093-92-4)
- Dasatinib Impurity 34 (CAS CATO-C4X-160734)
- Sitagliptin Impurity 53 HCl (CAS 849832-76-4(free base))
- 4-(pyridin-2-yl)piperazin-1-amine (CAS 40966-34-5)
- 3,6-dihydro-2H-pyran-2-carboxylic acid (CAS 116233-54-6)
- 7-Aminoisoquinoline-5,8-dione (CAS 118680-81-2)
- N,N-Diethyl-N-hydroxy-ethylenediamine (CAS 55845-75-5)
- methyl 5-{[(tert-butoxy)carbonyl]amino}-1,2-oxazole-3-carboxylate (CAS 1779756-98-7)
- 4-Ethynyl-2-fluorobenzonitrile (CAS 167858-57-3)
- Glucagon receptor antagonist I (CAS 438618-32-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com