【管制禁售】Etomidate EP impurity BHCI CAS 35944-74-2
| CAS No. | 35944-74-2 |
| Molecular Formula | C13H14N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies 【管制禁售】Etomidate EP impurity BHCI (CAS 35944-74-2), a pharmacopoeial impurity reference standard (molecular formula C13H14N2O2HCl, MW 266.73 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 【管制禁售】Etomidate EP impurity BHCI is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 266.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H14N2O2 HCl |
| Molecular Weight | 266.73 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Etomidate Standards
- Etomidate Impurity 23 (CAS 112421-33-7)
- Etomidate Racemate (CAS 15301-65-2)
- Etomidate Impurity 75 (CAS 1567838-90-7)
- Etomidate Impurity 6 (CAS 23785-21-9)
- Etomidate Impurity N15 (CAS 2433776-55-5)
- Etomidate Impurity 50 (CAS 2626887-15-6)
- Etomidate Impurity N3 (CAS 31502-34-8)
- Etomidate EP Impurity A (CAS 3157-27-5)
Recommended Standards
- Lusutrombopag Impurity 57 (CAS CATO-C4X-208457)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
- Eltrombopag Impurity 31 (CAS 25487-66-5)
- 2-bromo-N,N-dimethyl-ethanamine (CAS 5459-68-7)
- N'-[(1E)-[2-(2,6-Dimethylmorpholin-4-yl)-1,3-thiazol-5-yl]methylidene]-2-hydroxybenzohydrazide (CAS 477868-57-8)
- 5-Fluoro-1,2,3,4-tetrahydroquinoline-2-carboxylic acid (CAS 511234-65-4)
- 1-(Chloromethyl)naphthalene (CAS 86-52-2)
- N-[2-(2-Isopropyl-5-methylphenoxy)ethyl]-4-propoxyaniline (CAS 1040688-84-3)
- 4-Chloro-2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepine (CAS 1366003-67-9)
- D-Tyr10-Tirzepatide (CAS CATO-CPTD788922)
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