4-Hydroxy-8-methylquinoline-3-carboxylic acid CAS 35966-17-7
| CAS No. | 35966-17-7 |
| Molecular Formula | C11H9NO3 |
| Molecular Weight | 203.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Hydroxy-8-methylquinoline-3-carboxylic acid (CAS 35966-17-7), a certified reference material (molecular formula C11H9NO3, MW 203.19 g/mol) for analytical method development and quality control.
4-Hydroxy-8-methylquinoline-3-carboxylic acid (C11H9NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Hydroxy-8-methylquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9NO3 |
| Molecular Weight | 203.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- 2-hydroxy-7-methylquinoline-3-carboxylic acid (CAS 101133-49-7)
- 2-Hydroxy-7-methoxyquinoline-3-carboxaldehyde (CAS 101382-55-2)
- 7-Hydroxy-2-methylquinoline-3-carboxylic acid (CAS 103853-86-7)
- 8-Hydroxy-2-methylquinoline-5-carboxylic acid (CAS 103853-87-8)
- 4-Hydroxy-3-nitrobenzene acetic acid (CAS 10463-20-4)
- 2-Hydroxy-8-methoxyquinoline-3-carbaldehyde (CAS 112584-01-7)
- N-Hydroxy-N-phenylfuran-3-carboxamide (CAS 1137-48-0)
- 1-Acetyl-3-hydroxy-1H-indole-2-carbaldehyde (CAS 133593-40-5)
Recommended Standards
- 4-Hydroxy-8-methyl-2-oxo-1,2-dihydroquinoline-3-carbaldehyde (CAS 291518-16-6)
- 4-Hydroxyquinoline-2-acetic acid (CAS 857206-59-8)
- 4-Hydroxy-7-methylquinoline-3-carboxylic Acid (CAS 256923-25-8)
- 4-Methoxy-[1,3]dioxolo[4,5-g]isoquinoline (CAS 5361-66-0)
- 1-Propyl-1h-1,2,3-triazole-4-carboxylic acid (CAS 1266840-44-1)
- N-(pyrrolidin-3-yl)benzamide hydrochloride (CAS 57152-17-7)
- (S)-1-(3-bromo-5-fluoropyridin-2-yl)ethan-1-amine (CAS 1932587-71-7)
- 4-(Aminomethyl)-3,4-dimethylhexan-3-ol (CAS 1522856-58-1)
- N-((1-Isopropyl-1H-pyrazol-4-yl)methyl)-1,3-dimethyl-1H-pyrazol-4-amine hydrochloride (CAS 1856051-58-5)
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- 1-ethynyl-4-methylcyclohexane (CAS 1566918-82-8)
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