4-Methoxy-[1,3]dioxolo[4,5-g]isoquinoline CAS 5361-66-0
| CAS No. | 5361-66-0 |
| Molecular Formula | C11H9NO3 |
| Molecular Weight | 203.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-Methoxy-[1,3]dioxolo[4,5-g]isoquinoline (CAS 5361-66-0) is a high-purity analytical reference standard with the molecular formula C11H9NO3 and a molecular weight of 203.19 g/mol.
The molecular framework of 4-Methoxy-[1,3]dioxolo[4,5-g]isoquinoline (C11H9NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9NO3 |
| Molecular Weight | 203.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Methoxy Standards
- 4-Methoxy-[1,3]dioxolo[4,5-h]isoquinoline (CAS 110103-20-3)
- 8-Methoxy-2-methylquinoline-5,6-dione (CAS 120051-18-5)
- 4-(2-Methoxy-acetyl)-morpholine-3-carboxylic acid (CAS 1316219-80-3)
- 1-Methoxy-3-nitronaphthalene (CAS 13802-40-9)
- 143571-91-9 7-Methoxy-2-oxo-1,2-dihydroquinoline-3-carbaldehyde AZ0001-0360 (CAS 143571-91-9)
- 8-Methoxy-2-oxo-1,2-dihydroquinoline-4-carbaldehyde (CAS 143571-92-0)
- 5-methoxy-2-nitrobenzoic acid (CAS 1882-69-5)
- 1-Methoxy-4-nitronaphthalene (CAS 4900-63-4)
Recommended Standards
- 4-Hydroxyquinoline-2-acetic acid (CAS 857206-59-8)
- 4-methoxyquinoline-3-carboxylic acid (CAS 74557-74-7)
- 4-Hydroxy-8-methylquinoline-3-carboxylic acid (CAS 35966-17-7)
- 4-methyl-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid (CAS 56661-82-6)
- 1-Benzyl-4-(2-(trifluoromethyl)-pyridin-3-yl)piperazine (CAS 1774898-22-4)
- 4-Fluorocyclohex-3-en-1-amine (CAS 675112-72-8)
- (Z)-Dec-3-en-1-yl acetate (CAS 81634-99-3)
- Z-Phe-Val-Arg-pNA HCl (CAS 69716-00-3)
- Ethyl 2-bromo-5-cyano-3-methoxybenzoate (CAS 1807027-20-8)
- 6-(Trifluoromethyl)isoquinoline-1-carboxylic acid (CAS 2225878-86-2)
- 6-Methyl-4a,7a-dihydrothieno[2,3-d]pyrimidin-4(3H)-one (CAS 1273578-08-7)
- 4-Chloro-N-(6-(4-chlorophenyl)-2-oxo-2H-pyran-3-yl)benzamide (CAS 338747-88-9)
- Methyl (E)-3-(3,5-Difluoro-4-formylphenyl)acrylate (CAS 1639042-39-9)
- Semaglutide impurity 227 (CAS CATO-C4X-2226227)
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