6,8-Dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid CAS 35973-27-4
| CAS No. | 35973-27-4 |
| Molecular Formula | C10H5Cl2NO3 |
| Molecular Weight | 258.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6,8-Dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (C10H5Cl2NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
6,8-Dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 35973-27-4) is a high-purity analytical reference standard with the molecular formula C10H5Cl2NO3 and a molecular weight of 258.06 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6,8-Dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5Cl2NO3 |
| Molecular Weight | 258.06 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dichloro Standards
- 6,8-Dichloro-2-oxo-2H-chromene-3-carboxamide (CAS 101166-95-4)
- 6,8-Dichloro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (CAS 134785-79-8)
- 4-(4,6-Dichloro-1,3,5-triazin-2-yl)benzene-1,3-diol (CAS 150238-76-9)
- 2-(4,7-Dichloro-3-indolyl)-2-oxoacetic Acid (CAS 1514155-85-1)
- 5,7-Dichloro-4-hydroxyquinoline-3-carboxylic acid (CAS 171850-30-9)
- 4,5-Dichloro-1-(4-nitrophenyl)-1H-imidazole (CAS 649579-09-9)
- 5,8-Dichloro-4-hydroxyquinoline-3-carboxylic acid (CAS 35973-26-3)
- 6,7-Dichloro-4-hydroxyquinoline-3-carboxylic acid (CAS 26893-20-9)
Recommended Standards
- 6,8-Dichloro-2-hydroxyquinoline-4-carboxylic acid (CAS 50504-24-0)
- 6,9-Dichloro-2,3-dihydro-4H-1-oxa-3a,5,8-triazaphenalen-4-one (CAS 2883421-75-6)
- 6,7-Dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 51726-82-0)
- 6-Iodo-2-methylimidazo[1,2-a]pyridine (CAS 860722-41-4)
- 2-(2-Chloro-4-methoxyphenoxy)acetic acid (CAS 714250-83-6)
- 4-methoxyoxane-4-carbaldehyde (CAS 175982-76-0)
- 6,7-Dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-carbaldehyde (CAS 1706433-45-5)
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- 2-Chloro-4-ethoxy-6-(trifluoromethyl)pyrimidine (CAS 114963-95-0)
- 2-Aminonaphthalen-1-ol (CAS 606-41-7)
- Hexyl Glyoxylate (CAS 52709-43-0)
- 4-{2-[4-(1-Methyl-1-phenylethyl)phenoxy]-ethyl}piperidine hydrochloride (CAS 1220020-23-4)
- 5,6,7,8-Tetrahydro-2H-isoxazolo[4,5-d]azepin-3(4H)-one (CAS 53658-58-5)
- Des-Val23-Tirzepatide (CAS CATO-CPTD788950)
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