5,8-Dichloro-4-hydroxyquinoline-3-carboxylic acid CAS 35973-26-3
| CAS No. | 35973-26-3 |
| Molecular Formula | C10H5Cl2NO3 |
| Molecular Weight | 258.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5,8-Dichloro-4-hydroxyquinoline-3-carboxylic acid (C10H5Cl2NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
5,8-Dichloro-4-hydroxyquinoline-3-carboxylic acid (CAS 35973-26-3), molecular formula C10H5Cl2NO3 and molecular weight 258.06 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5,8-Dichloro-4-hydroxyquinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5Cl2NO3 |
| Molecular Weight | 258.06 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dichloro Standards
- 6,8-Dichloro-2-oxo-2H-chromene-3-carboxamide (CAS 101166-95-4)
- 6,8-Dichloro-4-oxo-1,4-dihydroquinoline-2-carboxylic acid (CAS 134785-79-8)
- 4-(4,6-Dichloro-1,3,5-triazin-2-yl)benzene-1,3-diol (CAS 150238-76-9)
- 2-(4,7-Dichloro-3-indolyl)-2-oxoacetic Acid (CAS 1514155-85-1)
- 5,7-Dichloro-4-hydroxyquinoline-3-carboxylic acid (CAS 171850-30-9)
- 4,5-Dichloro-1-(4-nitrophenyl)-1H-imidazole (CAS 649579-09-9)
- 6,7-Dichloro-4-hydroxyquinoline-3-carboxylic acid (CAS 26893-20-9)
- 6,7-Dichloro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 51726-82-0)
Recommended Standards
- 5-(3,4-Dichlorophenyl)isoxazole-3-carboxylic Acid (CAS 876710-49-5)
- 5-Bromo-1-(difluoromethyl)isoquinoline (CAS 2169656-77-1)
- 5-(2,5-Dichlorophenyl)isoxazole-3-carboxylic Acid (CAS 953724-37-3)
- 5-Bromo-8-(difluoromethyl)quinoline (CAS 2248394-00-3)
- 4,5-Dichloroindole-3-acetic Acid (CAS 98639-99-7)
- 4-[(E)-{[3-(trifluoromethyl)phenyl]methylidene}amino]phenyl 2,4,6-trimethylbenzene-1-sulfonate (CAS 329778-31-6)
- (2R,3R,4S,5R,6R)-2-(hydroxymethyl)-6-(3-nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triol (CAS 52571-71-8)
- 9,9'-Spirobi[fluoren]-4-amine (CAS 1579281-06-3)
- Thallium(I) sulfide (CAS 1314-97-2)
- N-Pyridin-4-yl-guanidine dihydrochloride (CAS 1286277-20-0)
- (4-(Benzyl(methyl)amino)phenyl)methanol (CAS 131719-59-0)
- 2-(3-Methoxyphenyl)quinazolin-4(3H)-one (CAS 56071-04-6)
- (2,5-Dichlorothiazol-4-yl)methanol (CAS 1823921-75-0)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
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