N-(5-chloro-2-hydroxyphenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide CAS 361369-00-8
| CAS No. | 361369-00-8 |
| Molecular Formula | C17H15ClN2O3 |
| Molecular Weight | 330.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 330.77 g/mol gives N-(5-chloro-2-hydroxyphenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(5-chloro-2-hydroxyphenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide (CAS 361369-00-8), molecular formula C17H15ClN2O3 and molecular weight 330.77 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(5-chloro-2-hydroxyphenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide (C17H15ClN2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H15ClN2O3 |
| Molecular Weight | 330.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
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Recommended Standards
- N-(4-Chlorobenzyl)-3-(2-oxobenzo[d]oxazol-3(2H)-yl)propanamide (CAS 851988-91-5)
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- Ethyl 3-[(2-chlorophenyl)methyl]-2-oxo-2,3-dihydro-1H-1,3-benzodiazole-1-carboxylate (CAS 339013-53-5)
- Tivozanib Impurity 3 (CAS CATO-C4X-34003)
- 7-Methoxy-3-methyl-5-tosyl-2,3,4,5-tetrahydro-1H-phospholo[2,3-c]quinoline 3-oxide (CAS 84779-95-3)
- 4-(Piperidin-4-yl)-1,3-oxazolidin-2-one (CAS 1774896-41-1)
- 5-(Chloro(4-(trifluoromethyl)phenyl)methyl)benzo[d][1,3]dioxole (CAS 1417543-27-1)
- 5-(Diethoxymethyl)-2-mercapto-3-phenyl-3,5-dihydro-4H-imidazol-4-one (CAS 1171634-02-8)
- (3-Bromo-4-methoxyphenyl)methanol (CAS 38493-59-3)
- Boc-Dab(Z)-OH · DCHA (CAS 16947-89-0)
- 3-Ethoxy-2,6-difluoroaniline hydrochloride (CAS 1423029-39-3)
- ((1S,4R,5S)-spiro[bicyclo[2.2.1]Heptane-7,1'-cyclopropan]-2-en-5-yl)methanamine (CAS 1820580-65-1)
- 4-(Dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-amine (CAS 7520-92-5)
- Exenatide Acetate (CAS 141732-76-5)
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