Tivozanib Impurity 3 CAS CATO-C4X-34003
| CAS No. | CATO-C4X-34003 |
| Molecular Formula | C17H15ClN2O3 |
| Molecular Weight | 330.77 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Tivozanib Impurity 3 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 330.77 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Tivozanib Impurity 3 (CAS CATO-C4X-34003, C17H15ClN2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tivozanib Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H15ClN2O3 |
| Molecular Weight | 330.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tivozanib Standards
- Tivozanib Impurity 29 (CAS CATO-C4X-340029)
- Tivozanib Impurity 5 (CAS CATO-C4X-34005)
- Tivozanib Impurity 17 (CAS CATO-C4X-340017)
- Tivozanib Impurity 4 (CAS CATO-C4X-34004)
- Tivozanib Impurity 2 (CAS CATO-C4X-34002)
- Tivozanib Impurity 7 (CAS CATO-C4X-34007)
- Tivozanib Impurity 6 (CAS CATO-C4X-34006)
- Tivozanib Impurity 24 (CAS CATO-C4X-340024)
Recommended Standards
- N-(4-chlorophenyl)-4-(3,5-dimethyl-1H-pyrazol-1-yl)-6-hydrazinyl-1,3,5-triazin-2-amine (CAS 1158377-11-7)
- N-(5-chloro-2-hydroxyphenyl)-5-oxo-1-phenylpyrrolidine-3-carboxamide (CAS 361369-00-8)
- 7-Acetamido-d3 Clonazepam (1.0mg/ml in Acetonitrile) (CAS 1330166-04-5)
- N-(4-Chlorobenzyl)-3-(2-oxobenzo[d]oxazol-3(2H)-yl)propanamide (CAS 851988-91-5)
- Vonoprazan Fumarate Impurity 92 (CAS CATO-C4X-102092)
- Mirogabalin Impurity 2 (CAS CATO-C4X-29242)
- Iomeprol Impurity 4 (CAS 2068038-50-4)
- Rilpivirine Amide (CAS 500288-66-4)
- 1-(2-Chlorophenyl)-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 338979-06-9)
- 3-Amino-4-Cyclohexyl-Benzoic Acid Methyl Ester (CAS 191287-06-6)
- Potassium Bisperoxo(pyridine-2-carboxylato)oxovanadate (CAS 68782-46-7)
- Arenobufagin 3-hemisuberate (CAS 30219-16-0)
- Methyl 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-3-carboxylate hydrochloride (CAS 2137768-58-0)
- Acetyl Hexapeptide-38 (CAS 1400634-44-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com