Labetalol Impurity 8 CAS 36256-45-8
| CAS No. | 36256-45-8 |
| Molecular Formula | C10H9BrO4 |
| Molecular Weight | 273.08 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C10H9BrO4, Labetalol Impurity 8 contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 273.08 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Labetalol Impurity 8 (CAS 36256-45-8), a pharmacopoeial impurity reference standard (molecular formula C10H9BrO4, MW 273.08 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Labetalol Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9BrO4 |
| Molecular Weight | 273.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Br-containing |
Related Labetalol Standards
- Labetalol Impurity 61 (CAS CATO-C4X-246661)
- Labetalol Impurity 54 (CAS CATO-C4X-246654)
- Labetalol Impurity 20 (CAS 73866-23-6)
- Labetalol Impurity 79 (CAS CATO-C4X-246679)
- Labetalol Impurity 30 (CAS CATO-C4X-246630)
- Labetalol Impurity 64 (CAS CATO-C4X-246664)
- Labetalol Impurity 32 (CAS 345933-79-1)
- Labetalol Impurity 51 (CAS CATO-C4X-246651)
Recommended Standards
- Terbutaline impurity 131 (CAS CATO-C4X-1183131)
- 4,4,5,5-Tetramethyl-2-((4-nitrophenyl)ethynyl)-1,3,2-dioxaborolane (CAS 1005000-20-3)
- 4742AE 51665-84-0 C10H9BrO4 Methyl 2-(6-bromo-2H-1,3-benzodioxol-5-yl)acetate (CAS 51665-84-0)
- 8-Bromo-7-ethyl-3,7-dihydro-3-methyl-1H-purine-2,6-dione (CAS 101071-96-9)
- Gliquidone Impurity 5 (CAS 1314701-46-6)
- Phenoxybenzamine Impurity 3 (CAS 2512203-93-7)
- Vazegepant Impurity 40 (CAS CATO-C4X-320040)
- 2-(4-(1H-1,2,4-triazol-5-yl)-1H-pyrazol-1-yl)-3-chloro-5-(trifluoromethyl)pyridine (CAS 321526-20-9)
- Tert-butyl 4-(3-fluorobenzamido)piperidine-1-carboxylate (CAS 1233955-01-5)
- 1-(2,3-dimethylphenyl)hexahydropyrimidine-2,4-dione (CAS 871504-33-5)
- 2-(2-hydroxyphenyl)acetohydrazide (CAS 22446-43-1)
- 2-(Isocyanomethyl)-5-methylfuran (CAS 1031256-45-7)
- 1,4-Dichloro-2,5-dinitrobenzene (CAS 17488-25-4)
- Boc-Cholecystokinin Octapeptide (desulfated) (A-1295.0001) (CAS 25687-34-7)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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