2-(4-(1H-1,2,4-triazol-5-yl)-1H-pyrazol-1-yl)-3-chloro-5-(trifluoromethyl)pyridine CAS 321526-20-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-(1H-1,2,4-triazol-5-yl)-1H-pyrazol-1-yl)-3-chloro-5-(trifluoromethyl)pyridine.

2-(4-(1H-1,2,4-triazol-5-yl)-1H-pyrazol-1-yl)-3-chloro-5-(trifluoromethyl)pyridine (CAS 321526-20-9), molecular formula C11H6ClF3N6 and molecular weight 314.65 g/mol, is a CATO reference standard with documented purity and traceability.

2-(4-(1H-1,2,4-triazol-5-yl)-1H-pyrazol-1-yl)-3-chloro-5-(trifluoromethyl)pyridine (C11H6ClF3N6) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(4-(1H-1,2,4-triazol-5-yl)-1H-pyrazol-1-yl)-3-chloro-5-(trifluoromethyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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