Tris(3-aminophenyl)phosphine oxide CAS 36357-49-0
| CAS No. | 36357-49-0 |
| Molecular Formula | C18H18N3OP |
| Molecular Weight | 323.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Tris(3-aminophenyl)phosphine oxide (CAS 36357-49-0) is a high-purity analytical reference standard with the molecular formula C18H18N3OP and a molecular weight of 323.33 g/mol.
The molecular framework of Tris(3-aminophenyl)phosphine oxide (C18H18N3OP) is characterized by a steroid core, an amide group, organophosphorus functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H18N3OP |
| Molecular Weight | 323.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Nitrogen Atoms | 3 |
Related Tris Standards
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Recommended Standards
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- Insulin Pork(≥27 USP units/mg) (CAS 12584-58-6)
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