2,4-Difluoro-6-nitroaniline CAS 364-30-7
| CAS No. | 364-30-7 |
| Molecular Formula | C6H4F2N2O2 |
| Molecular Weight | 174.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2,4-Difluoro-6-nitroaniline (CAS 364-30-7), a certified reference material (molecular formula C6H4F2N2O2, MW 174.10 g/mol) for analytical method development and quality control.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2,4-Difluoro-6-nitroaniline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 174.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4F2N2O2 |
| Molecular Weight | 174.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoro Standards
- 3,5-Difluoro-4-nitroaniline (CAS 122129-79-7)
- 2,4-Difluoro-5-nitroaniline (CAS 123344-02-5)
- 2,2-Difluoro-2-(pyrimidin-5-yl)acetic acid (CAS 1250738-18-1)
- 2,5-Difluoro-4-hydroxybenzoic acid (CAS 146781-23-9)
- 2,5-Difluoro-4-nitroaniline (CAS 1542-36-5)
- 2,5-Difluoro-3-nitroaniline (CAS 1699538-79-8)
- 2,3-Difluoro-4-hydroxybenzoic Acid (CAS 175968-39-5)
- 2,3-Difluoro-4-nitroaniline (CAS 1781140-23-5)
Recommended Standards
- 2,4-Difluoro-5-hydroxybenzoic acid (CAS 91659-22-2)
- 2,5-Difluoro-3,4-dihydroxybenzaldehyde (CAS 959216-64-9)
- 2,4-Difluoro-3-hydroxybenzoic acid (CAS 91659-08-4)
- 2,5-Difluoro-3-hydroxybenzoic acid (CAS 749230-40-8)
- 6-(4-Chloro-1H-pyrazol-1-yl)pyridin-3-amine (CAS 1006961-40-5)
- (2-Nitro-4-trifluoromethyl-phenylamino)-aceticacid (CAS 1428-53-1)
- Ethyl 1-(pyrimidin-4-yl)-1H-imidazole-4-carboxylate (CAS 1389313-33-0)
- 3-Allyl-1-methyl-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 1047652-27-6)
- 1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-4-one (CAS 937604-44-9)
- 3-Propylidenepyrrolidine (CAS 1563461-47-1)
- Ethyl 7-bromo-1-ethyl-1,3-benzodiazole-5-carboxylate (CAS 1437794-87-0)
- 1-Cycloocten-1-ol 1-Acetate (CAS 14478-13-8)
- 2-(Hydroxyamino)-2-oxoethylphosphonic acid, 90% (CAS 89873-30-3)
- D-[Thr]7-Liraglutide (CAS CATO-C4X-199237)
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