2-(4-Chlorophenoxy)-N,N-diphenylacetamide CAS 364383-40-4
| CAS No. | 364383-40-4 |
| Molecular Formula | C20H16ClNO2 |
| Molecular Weight | 337.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(4-Chlorophenoxy)-N,N-diphenylacetamide (C20H16ClNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-(4-Chlorophenoxy)-N,N-diphenylacetamide (CAS 364383-40-4) is a high-purity analytical reference standard with the molecular formula C20H16ClNO2 and a molecular weight of 337.80 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H16ClNO2 |
| Molecular Weight | 337.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenoxy Standards
- 7-(4-Chlorophenoxy)-3-phenyl-2,3-dihydro-1H-inden-1-ol (CAS 337921-73-0)
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Recommended Standards
- 2-(4-(4-Chlorophenyl)-2-methyl-3-oxo-1,2,4-oxadiazolidin-5-yl)-N-cyclopentylacetamide (CAS 478063-81-9)
- 2-(6-Chloro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)ethyl cyclohexanecarboxylate (CAS 865658-24-8)
- 2-([1,1'-Biphenyl]-4-yloxy)-N-(3-chlorophenyl)acetamide (CAS 302550-91-0)
- 2-Methyl-4-(4-methyl-1,1-dioxido-3-oxoisothiazolidin-2-yl)benzenesulfonyl chloride (CAS 927997-24-8)
- 4-((4-Chlorophenyl)thio)-N-(2,6-diethylphenyl)-3-nitrobenzamide (CAS 303988-26-3)
- 1,3-Di(pyrrolidin-1-yl)prop-2-ene-1-thione (CAS 15182-52-2)
- (1R,3S)-N-((4-cyano-2-(trifluoromethyl)phenyl)methyl)-3-((4-methyl-6-(methylamino)-1,3,5-triazin-2-yl)amino)cyclohexane-1-carboxamide (CAS 1142090-23-0)
- Azidotributyltin(IV), 95% (CAS 17846-68-3)
- Succinimidyl-p-nitrophenylacetate (CAS 68123-33-1)
- 4′-Bromo-4-mercaptobiphenyl (CAS 220805-21-0)
- 2-Amino-N-(2,3-dimethylphenyl)acetamide (CAS 885460-32-2)
- (S)-tert-Butyl (2-oxo-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)carbamate (CAS 175211-39-9)
- 2-Chloro-5-(3-ethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)aniline (CAS 945314-60-3)
- Tau Peptide (74-102) (Exon 3/Insert 2 Domain) trifluoroacetate salt (CAS 1322695-34-0)
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