4-(4-Chlorophenoxy)-3,5-difluorobenzenesulfonyl chloride CAS 549547-34-4
| CAS No. | 549547-34-4 |
| Molecular Formula | C12H6Cl2F2O3S |
| Molecular Weight | 339.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(4-Chlorophenoxy)-3,5-difluorobenzenesulfonyl chloride (CAS 549547-34-4), molecular formula C12H6Cl2F2O3S and molecular weight 339.14 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 4-(4-Chlorophenoxy)-3,5-difluorobenzenesulfonyl chloride is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 339.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(4-Chlorophenoxy)-3,5-difluorobenzenesulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H6Cl2F2O3S |
| Molecular Weight | 339.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Chlorophenoxy Standards
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- 1-(2-Chloro-6-methoxyphenyl)ethanol (CAS 1175300-41-0)
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- 2-methoxy-2-(3-methoxyphenyl)acetic acid (CAS 1832647-27-4)
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Why CATO?
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