| CAS No. | 364765-44-6 |
| Molecular Formula | C22H26F2 |
| Molecular Weight | 328.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
The occurrence of 2,3-Difluoro-4-methyl-4'-((1s,4r)-4-propylcyclohexyl)-1,1'-biphenyl is closely related to fluorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,3-Difluoro-4-methyl-4'-((1s,4r)-4-propylcyclohexyl)-1,1'-biphenyl (CAS 364765-44-6), molecular formula C22H26F2 and molecular weight 328.44 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2,3-Difluoro-4-methyl-4'-((1s,4r)-4-propylcyclohexyl)-1,1'-biphenyl (C22H26F2) contains fluorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 328.44 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,3-Difluoro-4-methyl-4'-((1s,4r)-4-propylcyclohexyl)-1,1'-biphenyl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C22H26F2 |
| Molecular Weight | 328.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |