1,2,4-Trifluorobenzene CAS 367-23-7

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,2,4-Trifluorobenzene.

1,2,4-Trifluorobenzene (CAS 367-23-7), molecular formula C6H3F3 and molecular weight 132.08 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to fluorine substitution, an aromatic ring system, 1,2,4-Trifluorobenzene is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 132.08 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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