2-(Trifluoromethyl)-1H-benzo[d]imidazol-5-amine CAS 3671-66-7
| CAS No. | 3671-66-7 |
| Molecular Formula | C8H6F3N3 |
| Molecular Weight | 201.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-(Trifluoromethyl)-1H-benzo[d]imidazol-5-amine (CAS 3671-66-7) is a high-purity analytical reference standard with the molecular formula C8H6F3N3 and a molecular weight of 201.15 g/mol.
Structurally, 2-(Trifluoromethyl)-1H-benzo[d]imidazol-5-amine (C8H6F3N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 201.15 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6F3N3 |
| Molecular Weight | 201.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 6-(Trifluoromethyl)-1H-indazol-5-amine (CAS 1000373-75-0)
- 7-(Trifluoromethyl)imidazo[1,5-a]pyridin-3-amine (CAS 1005514-81-7)
- 7-Trifluoromethyl-1H-benzoimidazol-2-ylamine (CAS 10057-45-1)
- 2-(Trifluoromethyl)-1H-indol-4-ol (CAS 1016241-93-2)
- 4-(Trifluoromethyl)-1H-indazol-6-amine (CAS 1169788-34-4)
- 2-(trifluoromethyl)-1H-Pyrrolo[2,3-b]pyridin-5-amine (CAS 1186502-40-8)
- 6-(Trifluoromethyl)-1H-pyrrolo[3,2-b]pyridin-3-amine (CAS 1190311-51-3)
- 5-(Trifluoromethyl)-1H-pyrrolo[3,2-b]pyridin-3-amine (CAS 1190319-60-8)
Recommended Standards
- 2-(4-(Trifluoromethyl)phenoxy)acetonitrile (CAS 874804-02-1)
- 2-(Trifluoromethyl)-1H-indol-5-ol (CAS 288383-62-0)
- 2-(4-(Trifluoromethoxy)phenyl)acetonitrile (CAS 49561-96-8)
- 2-[3-(trifluoromethyl)phenoxy]acetonitrile (CAS 2145-31-5)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-cyclopropyl-4-methoxybutanoic acid (CAS 2000175-42-6)
- 2-Chloro-n-(2-cyanoethyl)acetamide (CAS 17756-81-9)
- 1-(4-Chlorophenyl)-5-(propan-2-yl)-1h-pyrazole-4-carboxylic acid (CAS 187998-36-3)
- Methyl 3-(1-Tetrazolyl)benzoate (CAS 309279-57-0)
- Hydroxyzine Impurity 1 (CAS 628-89-7)
- n-[3-(carbamoylamino)phenyl]acetamide (CAS 720670-20-2)
- 2-Amino-2-(benzo[d][1,3]dioxol-5-yl)acetic acid hydrochloride (CAS 86068-94-2)
- Methyl 3-(2-hydroxyethyl)cyclobutane-1-carboxylate (CAS 2231673-89-3)
- 3-(2-Chloro-8-methylquinolin-3-yl)-5-propyl-1,2,4-oxadiazole (CAS 1142201-69-1)
- Des-[Gly]31-Semaglutide(x TFA Salt) (CAS 873874-39-6(free base))
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