(2E)-2-Cyano-3-(4-methoxyphenyl)-N-(pyridin-2-yl)prop-2-enamide CAS 367278-79-3

Purity 97%+In StockPharmaceutical Standards
CAS No.367278-79-3
Molecular FormulaC16H13N3O2
Molecular Weight279.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2E)-2-Cyano-3-(4-methoxyphenyl)-N-(pyridin-2-yl)prop-2-enamide CAS 367278-79-3 chemical structure

Description

The occurrence of (2E)-2-Cyano-3-(4-methoxyphenyl)-N-(pyridin-2-yl)prop-2-enamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(2E)-2-Cyano-3-(4-methoxyphenyl)-N-(pyridin-2-yl)prop-2-enamide (CAS 367278-79-3), molecular formula C16H13N3O2 and molecular weight 279.29 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, (2E)-2-Cyano-3-(4-methoxyphenyl)-N-(pyridin-2-yl)prop-2-enamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 279.29 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (2E)-2-Cyano-3-(4-methoxyphenyl)-N-(pyridin-2-yl)prop-2-enamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H13N3O2
Molecular Weight279.29 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms3

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