2-(3-Cyano-4-(4-fluorophenyl)-5,5-dimethylfuran-2(5H)-ylidene)malononitrile CAS 425604-51-9
| CAS No. | 425604-51-9 |
| Molecular Formula | C16H10FN3O |
| Molecular Weight | 279.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(3-Cyano-4-(4-fluorophenyl)-5,5-dimethylfuran-2(5H)-ylidene)malononitrile (CAS 425604-51-9) is a high-purity analytical reference standard with the molecular formula C16H10FN3O and a molecular weight of 279.27 g/mol.
The molecular framework of 2-(3-Cyano-4-(4-fluorophenyl)-5,5-dimethylfuran-2(5H)-ylidene)malononitrile (C16H10FN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(3-Cyano-4-(4-fluorophenyl)-5,5-dimethylfuran-2(5H)-ylidene)malononitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H10FN3O |
| Molecular Weight | 279.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 2-((2-(Furan-2-yl)-2-oxoethylidene)amino)benzenesulfonic acid (CAS 88847-01-2)
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- (S)-2-(2-Amino-3-(5-fluoro-1H-indol-3-yl)propanamido)acetic acid (CAS 918957-35-4)
- Streptavidin from Streptomyces avidinii (CAS 9013-20-1)
- 2-Piperidinecarboxylic acid, 1-(chlorocarbonyl)-, methyl ester (CAS 86264-78-0)
- Allyl benzyl(ethyl)carbamate (CAS 141577-33-5)
- 2-Cyano-2-(methoxyimino)acetic Acid (CAS 78325-17-4)
- Zolpidem Impurity 19 (CAS CATO-C4X-148619)
- 4-Bromo-5-ethyl-1h-pyrrole-2-carbaldehyde (CAS 1354783-30-4)
- Apalutamide Impurity 72 (CAS 1950587-19-5)
- Ethyl 1-(4-cyanophenyl)-1H-pyrazole-3-carboxylate (CAS 1707392-21-9)
- 5-Chloro-N-methylbenzo[d]oxazol-2-amine (CAS 64037-24-7)
- Anorexigenic Peptide (CAS 69275-10-1)
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