1,3-Bis(4-fluorophenyl)urea CAS 370-22-9
| CAS No. | 370-22-9 |
| Molecular Formula | C13H10F2N2O |
| Molecular Weight | 248.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1,3-Bis(4-fluorophenyl)urea (CAS 370-22-9), molecular formula C13H10F2N2O and molecular weight 248.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1,3-Bis(4-fluorophenyl)urea (C13H10F2N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1,3-Bis(4-fluorophenyl)urea under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H10F2N2O |
| Molecular Weight | 248.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Bis Standards
- (E)-[1-(4-Fluorophenyl)ethylidene][(6-fluoropyridin-2-yl)oxy]amine (CAS 338786-33-7)
- 1,2-Bis(2-fluorophenyl)-2-hydroxyethan-1-one (CAS 125652-30-4)
- 1,2-Bis(3-fluorophenyl)-2-hydroxyethan-1-one (CAS 66659-65-2)
- 2,2-Bis(3-fluorophenyl)acetic acid (CAS 927802-68-4)
- 2,2-Bis(4-fluorophenyl)acetic acid (CAS 361-63-7)
- 8-(4-Fluorophenyl)-2,6,7,8-tetrahydroimidazo[2,1-c][1,2,4]triazine-3,4-dione (CAS 1105190-03-1)
- 2-(3-(2-Fluorophenyl)-6-oxopyridazin-1(6H)-yl)acetic acid (CAS 1206119-33-6)
- 2-(4-(4-Fluorophenyl)-6-oxopyrimidin-1(6H)-yl)acetic acid (CAS 1286705-94-9)
Recommended Standards
- 1,1'-(Butane-1,4-diyl)bis(1H-pyrrole-2,5-dione) (CAS 28537-70-4)
- 1-[4-(Aminocarbonyl)phenyl]-5-oxopyrrolidine-3-carboxylic acid (CAS 885953-76-4)
- 1-(4-Nitrobenzyl)piperidine-2,4-dione (CAS 99539-92-1)
- 1H-Imidazole-4-carboxylic acid, 2,3-dihydro-1-(4-methoxyphenyl)-2-oxo- (CAS 64559-57-5)
- Emedastine N-Oxide (CAS 122484-65-5)
- 3-(Trifluoromethyl)quinoline-8-carboxylic acid (CAS 588702-66-3)
- (S)-5-Ethoxy-2,3-dihydro-1H-inden-1-amine hydrochloride (CAS 1312949-70-4)
- Decahydropyrrolo[3,4-b]pyrrolizin-6-ol (CAS 132414-56-3)
- 1-(4-Amino-3-chloro-5-fluoro-phenyl)-ethanone (CAS 56339-99-2)
- 6-Bromo-3-hydroxypyrazine-2-carboxylic acid (CAS 1260667-67-1)
- Diethyl (2,3-diphenylpyrido[3,4-b]pyrazine-5,7-diyl)dicarbamate (CAS 16335-96-9)
- 6-(tert-Butyl)-3-isopropylisothiazolo[3,4-d]pyrimidin-4(1H)-one (CAS 40915-86-4)
- (9-cis,15-cis)-β,β-Carotene (CAS 51364-07-9)
- Liraglutide Impurity 10 TFA Salt (CAS CATO-C4X-199210)
Why CATO?
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