1-(4-Amino-3-chloro-5-fluoro-phenyl)-ethanone CAS 56339-99-2

Purity 97%+In StockPharmaceutical Standards
CAS No.56339-99-2
Molecular FormulaC8H7ClFNO
Molecular Weight187.60 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(4-Amino-3-chloro-5-fluoro-phenyl)-ethanone CAS 56339-99-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 187.60 g/mol gives 1-(4-Amino-3-chloro-5-fluoro-phenyl)-ethanone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-(4-Amino-3-chloro-5-fluoro-phenyl)-ethanone (CAS 56339-99-2) is a high-purity analytical reference standard with the molecular formula C8H7ClFNO and a molecular weight of 187.60 g/mol.

The molecular framework of 1-(4-Amino-3-chloro-5-fluoro-phenyl)-ethanone (C8H7ClFNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(4-Amino-3-chloro-5-fluoro-phenyl)-ethanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H7ClFNO
Molecular Weight187.60 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1973
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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