8-Bromo-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one CAS 37040-46-3

Purity 97%+In StockPharmaceutical Standards
CAS No.37040-46-3
Molecular FormulaC9H9BrN2O
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

8-Bromo-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one CAS 37040-46-3 chemical structure

Description

The occurrence of 8-Bromo-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

8-Bromo-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one (CAS 37040-46-3), molecular formula C9H9BrN2OHCl and molecular weight 277.55 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 8-Bromo-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one (C9H9BrN2OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 8-Bromo-4,5-dihydro-1H-benzo[b][1,4]diazepin-2(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC9H9BrN2O HCl
Molecular Weight277.55 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1967
Halogen ContentCl/Br-containing
Nitrogen Atoms2

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